AUTHOR INDEX
Abbud, Eliyya, 434
Abraham, Soman N., 318
Aleveritis, Ellie, 305
Atalay, Habip, 267
Athyros, Vasilios G., 116
Aytekin, Faruk Onder, 267
Baase, Catherine, 67
Bairaktari, Eleni, 116
Bakken, Lori L., 123
Barilli, Angela Luciana, 26
Bayless, Kayla J., 414
Beharry, Kay D.A., 253
Berenji, Kambeez, 414
Bertoni, Roberto, 26
Bir, Ferda, 267
Blazhev, Alexander, 128
Bonow, Robert, 67
Bozdayi, Abdurrahman Mithat, 353
Bozkaya, Hakan, 353
Britigan, Bradley E., 143
Brunson, Charlie E., 434
Buchman, Alan L., 402
Burnett, John C., Jr, 378
Califf, Robert, 67
Campbell, Adam G., 201
Cariolou, Marios, 116
Cataliotti, Alessandro, 378
Catanese, Veronica, 67
Chen, Dali, 15
Christova, Petkama, 128
Cinar, Kubilay, 353
Cisler, Jason J., 402
Clancy, Carolyn M., 65
Cohen, Richard J., 82
Coiro, Vittorio, 26
Colleran, Kathleen M., 264
Cowen, Daniel S., 37
Crowley, William F., Jr, 425
Davis, George E., 414
de Bold, Adolfo J., 371
de Bold, Mercedes L. Kuroski, 371
Dekov, Dancho, 128
Delafontaine, Patrick, 135
Delsignore, Roberto, 26
Desai, Bijal D., 37
Dinges, Warren L., 15
Di Secli, Clelia, 26
Dobs, Adrian, 67
Dorovski, Plamen, 128
Dowdy, David, 192
Duann, Pu, 37
Duncan, Matthew J., 318
Elisaf, Moses S., 116
Erden, Esra, 353
Ergül, Ayça Arslan, 353
Ferrari, Carlo, 26
Feussner, John, 67
Finardi, Lorenzo, 26
Forrest, Kathy, 322
Frangos, John A., 246
Gallin, Elaine K., 73
Ganotakis, Manolis, 116
Garg, Abhimanyu, 15
Genel, Myron, 67
Glaser, John, 425
Godard, Michael, 135
Goebel, Jens, 322
Gramaglia, Irene, 246
Grenon, S. Marlene, 82
Guha, Bhuvana, 305
Guidot, David M., 235
Hart, C. Michael, 235
Hill, Joseph A., 414
Ho, Teh-Yuan, 37
Hörl, Walter H., 366
Hurwitz, Shelley, 82
Idilman, Ramazan, 353
Intaglietta, Marcos, 246
Ismail, Hassan M., 31, 305
Johnson, Stephen B., 192
Jordanova-Laleva, Pavlima, 128
Jotti, Gloria Saccani, 26
Kapoian, Toros, 37
Kaya, Seyda Ors, 267
Kenworthy, Anne K., 312
Keogh, Diane, 425
Kim, Christine, 82
Koytak, Elif Sare, 353
Kupersmith, Joel, 67
La Gioia, Daniele, 26
LeBlancq, Sylvie M., 73
Li, Guojie, 318
Li, Yangxin, 135
Lianos, Elias A., 37
Liberopoulos, Evagelos N., 116
Lichtenstein, Michael, 123
Logan, Barbara, 322
Markov, Angel K., 434
Metcalf, Jordan P., 292
Michelena, Hector I., 176
Mieczkowski, Alexandra, 322
Miltiadous, George A., 116
Minelli, Roberta, 26
Modanlou, Houchang D., 253
Nazir, Shoab A., 292
Nicoloff, George, 128
Njoku, Chinedu J., 347
Noiri, Eisei, 167
Nolan, Bridgid, 414
Oates, Jim C., 347
Olakanmi, Oyebode, 143
Olive, Kenneth, 305
Olson, Darin E., 201
Önder, Oğuz, 353
Onem, Gokhan, 267
Osman, Khidir, 434
Panja, Srinivas, 264
Patrick, Kennerly S., 347
Paveglio, Sara A., 201
Payne, Philip R.O., 192
Peterson, Dolores M., 15
Petrova, Chaika, 128
Pfortmiller, Deborah, 31
Porter, Marty H., 201
Ramsdell, Craig D., 82
Reame, Nancy, 67
Reece, E. Albert, 67
Richardson, Kenneth E., 414
Richmond, Scott R., 135
Rosenthal, Nadia, 135
Roszman, Thomas L., 322
Rothermel, Beverly A., 414
Ruiz, Philip, Jr, 347
Saçar, Mustafa, 267
Salahudeen, Abdulla K., 360
Sherwood, Louis, 67
Sheynberg, Natalie, 82
Simmons, Christina, 31
Skelton, Thomas N., 434
Slavkin, Harold, 67
Sloan, Susan, 305
Slutsky, Jean R., 65
Snell, Peter G., 15
Sobolewski, Peter, 246
Song, Yao-Hua, 135
Starr, Brian, 264
Starren, Justin B., 192
Stokes, John B., 143
Stubbs, Connie, 425
Sung, Nancy, 67
Tambunting, Francis, 253
Tannous, Paul, 414
Thulé, Peter M., 201
Tilson, Hugh, 67, 192
Tsukahara, Hirokazu, 167
Turisco, Fran, 425
Uzunalimoglu, Özden, 353
Valli, Maria Antonietta, 26
VanDecker, William A., 176
van der Heyde, Henri C., 246
Verdi, Hasibe, 353
Vesely, David L., 360
Waltzman, Joshua, 253
Weatherall, Paul T., 15
Williams, Gordon H., 82
Wills-Karp, Marsha, 322
Xiao, Xinshu, 82
Yurdaydin, Cihan, 353
Zaas, David, 318
Zhang, Jin-an, 201
SUBJECT INDEX
AAM. See American Academy of Microbiology
AAMC. See Association of American Medical Colleges
AAPS. See American Association of Pharmaceutical Scientists
ABCR. See Advisory Board for Clinical Research
Abraham, Edward, 392
Absorptiometry, 15-24
Academic health centers, 331-333, 425-433
ACRWH. See Advisory Committee on Research on Women's Health
Acute coronary syndromes, 178
Acute lung injury, 235-243
Acute myocardial infarction, 371-375
Acute renal failure, 366-369
Acute respiratory distress syndrome, 235-243
Ad. See Adenovirus
Adashi, Eli Y., 55
Adenocarcinomas, 361-363
Adenosine A3 receptor, 37-42
Adenosine triphosphate, 434-437
Adenovirus (Ad)
innate immune response to, 292-300
insulin gene therapy, 201-210
Advanced glycation end products, 167-174
Advisory Board for Clinical Research (ABCR), 229
Advisory Committee on Research on Women's Health (ACRWH), 228, 280
AEAbs. See Antielastin antibodies
AFMR. See American Federation for Medical Research
Ahlport, Kathryn N., 217-220
AIDS. See HIV (human immunodeficiency virus)
ALA. See American Lung Association
Albert Lasker Award for Basic Medical Research, 4-5
Albert Lasker Award for Clinical Medical Research, 4-5
Alcohol abuse, 235-243
Alcohol biomarkers, 214-216
Aldosterone, 378-382
Alternative medicine, 399-400
Alveolar epithelium, 235-243, 319-320
Alving, Barbara, 222, 331-333
Alzheimer's disease, 45-46, 388
American Academy of Microbiology (AAM), 111-112
American Association for Cancer Research, 386
American Association of Pharmaceutical Scientists (AAPS), 56
American Diabetes Association, 31-36
American Federation for Medical Research (AFMR), 312, 360, 391
American Lung Association (ALA), 273
Amgen, Inc., 386
Angiogenesis, 92, 340-341
Angiogram, 179-180
Anthropometry, 15-24
Antielastin antibodies (AEAbs), 128-133
Antimicrobial peptides, 294
Antman, Karen H., 107
Apolipoprotein E, 116-121
Apoptosis, mesangial cell, 37-42
Archived publications, 58, 226-227
Arnold, Janice Lee, 161
AS. See Atorvastatin
Association of American Medical Colleges (AAMC), 2, 7, 13-14, 59, 103
Atherosclerosis, 31-36, 177-178
Atorvastatin (AS), 31-36, 322-327
Atrial natriuretic peptides, 360-382
Axel, Richard, 5-6
Bacterial mucosal barrier, 318-321
Baker, Nicole Johnson, 281
Battey, James, 228-229
Benner, Steven A., 11, 12
Beta cells, 213
Bilirubin, 171-172
Biodefense, 155-156, 216-217, 287
Biomedical informatics, 192-198
Biomedical institutes, 61-62
Biomedical research, 123-127
Bladder epithelial cells, 319
Blood flow, 179
Bloom, Joseph D., 1
Body fat distribution, 15-24
Bond, Enriqueta C., 217-220
Boston University School of Medicine, 107
Botanical products, 227
Boyd-Ford, Valda, 281
Brain natriuretic peptide, 371-382
Breast adenocarcinoma, 363
Bristol-Myers Squibb Awards, 163, 281, 386
Bristol-Myers Squibb Oncology Fellowship in Clinical Cancer Research, 386
Bronchopulmonary dysplasia, 253-262
Brown-Friday, Janet O., 161
Brown University, 55
Buck, Linda, 5-6
Burroughs Wellcome Fund, 217-221
CAD. See Coronary artery disease
Cain, Joanna, 228
Calcineurin, 414-422
California Institute for Regenerative Medicine, 223, 345
Cancer
biology program, 14
clinical trials, 286
consumer liaison group, 64
nanotechnology in, 398-399
natriuretic peptides and, 360-363
obesity and, 400-401
research, 163, 398-399
stem cells and, 272-273
Carbamazepine, 164
Cardiac fibrosis, 380-382
Cardiac hypertrophy, 414-422
Cardioendocrine system, 82-90
Cardiomyocytes, 415
Cardiovascular cell therapy, 385
Cardiovascular disease, 373-374
Cardiovascular system, 82-90
Cathelecidins, 294-295
Caveolae, 315, 318-321
CDC. See Centers for Disease Control and Prevention
Center for Scientific Review, 159
Centers for Disease Control and Prevention (CDC), 95-97
Centers of Research Translation (CORT), 271-272
Chambon, Pierre, 4-5
Chapman, John E., 2
Charles E. Culpeper Scholarships in Medical Science, 217
C-HC. See Chronic hepatitis C
Children
diabetic, 128-133
Pediatric Heart Network, 154
Chinese medicine, 399, 400
Cholesterol, 31-36, 316
Chronic hepatitis C (C-HC), 26-29
Cicero, Theodore J., 223-224
CIF. See Complement inhibition factor
CIST. See Clinical Investigators Student Training (CIST) Forum
Clark, Christina, 281
Clark, Luther, 280
Clinical and Translational Science Awards (CTSAs), 438-439
Clinical Investigators Student Training (CIST) Forum, 3-4
Clinical research
Alving on, 332
Crowley on, 51-53
fellowships, 73-81, 290
information technology and, 192-198, 425-433
loan repayment program, 385
new General Clinical Research Center, 7
predoctorial training programs, 6, 47-48
support for, 288
task force on, 7
See alsospecific institutions, researchers, and fields of research
Clinical research curriculum awards (CRCA), 123-127
Cohen, Jordan J., 103
Collins, Scott D., 12
Columbia University, 282
Complementary medicine, 399-400
Complement inhibition factor (CIF), 128-133
Coney, Ponjola, 280
Conflict of interest, 57-58, 112, 228-229
Congestive heart failure, 371-375
COPR. See Council of Public Representatives
Cord blood stem cell bank, 228
Coronary angiogram, 179-180
Coronary artery disease (CAD), 31-36, 176-188, 305-310
Coronary blood flow, 179
Corr, Peter B., 113-115
CORT. See Centers of Research Translation
Costa, Gina L., 11
Council of Public Representatives (COPR), 281
Council on Competitiveness, 111
Crawford, Lester, 334
CRCA. See Clinical research curriculum awards
Crook, Errol, 159, 389-391
Crowley, William, 49-53
CTSAs. See Clinical and Translational Science Awards
Cyclic guanosine monophosphate, 360-363
Cytokines, 297
Dallas Heart Study, 101-102
Dal Pan, Gerald, 394
Davis, Ronald W., 12
DDCF. See Doris Duke Charitable Foundation
Defensins, 294
Dendritic cells, 296
DEXA. See Dual-energy x-ray absorptiometry
Diabetes
beta cell regeneration for, 213
in children, 128-133
glycemic control, 264-266
hyperlipidemia and, 31-36
L162V polymorphism and, 355
oxidative stress and, 167-174
prognosis, 185
type 1, 62-63, 92
Diclofenac sodium, 267-270
Dietary supplements, 227
DNA sequencing, 10-12
DNA synthesis, 360-363
Doris Duke Charitable Foundation (DDCF), 275-278
Doris Duke Clinical Research Fellowship Program, 73-81
Drew University, 394
Drexel University, 1
Drug safety, 61-62
Dual-energy x-ray absorptiometry (DEXA), 15-24
Dunaif, Andrea, 280
East Tennessee State University, 305-310
Eckhert, N. Lynn, 2
Ejection fraction, 178
Electrocardiogram, 434-437
Embryonic stem cells. See Stem cells
Endocrinology, 49
Enzyme-linked immunosorbent assay, 167-174
Epidermal growth factor, 402-410
Epilepsy, 164
Epithelial cells, 296-297, 318-321
Escherichia coli, 319
Estrogen, 305-310
Ethanol, 239-240
Ethics, 57-58, 340
Evans, Ronald M., 4, 5
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 31-36
Farrell, Philip M., 54
Fasting glucose, 31-36
Fatty acids, 167-174, 187-188
Fatty liver, 353-358
FDA. See Food and Drug Administration
FIC. See Fogarty International Center
Fischbach, Gerald, 282
Flack, John, 279
Flier, Jeffrey Scott, 161
Flow cytometry, 323
Fluorescence, 312-316
Fogarty International Center (FIC), 290, 396-397
Food and Drug Administration (FDA), 60, 95-97, 161, 290, 334, 395
Ford, Daniel, 335
Free antielastin antibodies, 128-133
Fugh-Berman, Adriane, 231
Gallin, Elaine, 275-278
Gallium, 143-152
Gastrin, 402-410
Gavin, James R. III, 232-234
GCRCs. See General clinical research centers
GD. See Graves' disease
General clinical research centers (GCRCs), 332-333
Gene(s)
database, 111-112, 164
insulin therapy, 201-210
predictive value, 164
studies, 62-63, 163
therapy, 109-110, 230
Genomes, 10-12, 93-94, 111-112, 166
Genomics, 93-94, 214-215
Genotyping, 7-8
Ghostwriting, 231
Gilman, Alfred, 279
Global health, 290, 396-397
Global Registry of Acute Coronary Events, 31-36
Glucagon-like peptide, 402-410
Glucose
impaired fasting, 31-36
uptake, 201-210
Glutathione, 235-243
Glycemic control, 264-266
Glycogen, 201-210
Glycogenolysis, 206
Glycosylphosphatidylinositol-anchored proteins, 315
GM-1 marker, 322-327
Goldman Philanthropic Partnerships, 217
Graves' disease (GD), 26-29
Gray, Paulette, 223
Green fluorescent protein, 312-316
Greengard, Paul, 105
Greenwalt, Tibor J., 283
Grieder, Franziska, 55-56
Growth factors, 402-410
Guanosine triphosphatase, 414-422
Guttmacher, Alan E., 12-13
Gynecologic Cancer Foundation, 386
Hall, Zack, 223
Harold Amos Medical Faculty Development Program, 232-234
Harvard School of Public Health, 56
Health and Human Services (HHS), 10, 59-60, 288
Health care
effectiveness, 65-71
information network, 342-343
report on inefficiencies, 341
Health information technology, 10
Health insurance, 67-71
Health Insurance Portability and Accountability Act (HIPAA), 285
Heart
failure, 378-382, 401
natriuretic peptides and, 371-382
Pediatric Heart Network, 154
Heart and Estrogen/Progestin Replacement Study, 305-310
Heat-related illnesses, 401
Hellmann, David, 336
Hematopoietic progenitor stem cells, 228
Hemoglobin, 246-250
Henrich, William L., 161
Hepatic insulin gene therapy, 201-210
Hepatitis C
chronic, 26-29
virus-related liver steatosis, 353-358
Hepatocyte growth factor, 409
Herbal supplements, 227
Herbert W. Nickens Awards, 13-14
HHMI. See Howard Hughes Medical Institute
HHS. See Health and Human Services
HIPAA. See Health Insurance Portability and Accountability Act
HIV (human immunodeficiency virus)
regional body fat distribution in, 15-24
Tri-Service AIDS Clinical Consortium, 94-95
vaccine, 401
Hobbs, Helen, 99-102
Hormone replacement therapy (HRT), 305-310
Host cells, 201-210
Howard Hughes Medical Institute (HHMI), 112, 165, 230
HRT. See Hormone replacement therapy
Human Genome Project, 50
Human immunodeficiency virus. See HIV
Human pluripotent stem cells, 226
Hyperlipidemia, 31-36, 305-310
Hypertrophy
cardiac, 414-422
skeletal muscle, 135-141
Hypothermia, 434-437
IGF-I. See Insulin-like growth factor I
IL-1. See Interleukin-1
IL-2. See Interleukin-2
IL-6. See Interleukin-6
IL-8. See Interleukin-8
IL-12. See Interleukin-12
Immune responses, 292-300
Immunoblotting, 324
Immunoprecipitation, 323-324
Impaired fasting glucose, 31-36
Imperiale, Michael, 337
Information technology, 10, 46-47, 192-198, 425-433
Innate immune response, 292-300
Innovation, 111
Insel, Richard, 106
Insel, Thomas, 229
Institute of Medicine (IOM), 12-13, 228
Institutional review boards (IRBs), 227
Insulin-like growth factor I (IGF-I), 135-141
Interferons, 26-29, 299
Interleukin-1, 297
Interleukin-2, 322-327
Interleukin-6, 298
Interleukin-8, 298
Interleukin-12, 298-299
Internal medicine, 288
IOM. See Institute of Medicine
IRBs. See Institutional review boards
Iron, 143-152
Ischemic cascade, 178-179
Ischemic heart disease, 176-188
Islet cells, 111, 329, 385
Isoprostanes, 347-351
JDRF. See Juvenile Diabetes Research Foundation
Jefferson Medical College, 335
Jensen, Elwood V., 4, 5
Johns Hopkins University School of Medicine, 335-336, 392
Jovanovich, Stevan B., 11
Ju, Jingyue, 11
Juvenile Diabetes Research Foundation (JDRF), 92, 329
Kast, Linda, 280
Keck School of Medicine, 224
Kelman, Charles, 4
Kerr, Mary E., 107
Kidney disease, 62-63, 366-369
Klag, Michael, 392
Knudson, Alfred G., Jr, 163-164
Koh, Howard, 56
Korsmeyer, Stanley, 225
Lateral diffusion, 312-316
LDL. See Low-density lipoprotein
Lee, James Weifu, 12
Left ventricular function, 186
Linares-Orama, Nicolas, 281
Lindquist, Cynthia, 281
Lindsay, Stuart, 12
Lipid abnormalities, 355
Lipid metabolism, 116-121
Lipid peroxide, 167-174
Lipid rafts, 312-316, 318-327
Lipids, 31-36
Lipodystrophy, 15-24
Liver
disease, 63-64
insulin gene therapy, 201-210
steatosis, 353-358
Lohman, Kenton, 11
L162V polymorphism, 355
Low-density lipoprotein (LDL), 31-36
Lung disease, 253-262, 273
Lung injury, 235-243
Lupus nephritis, 347-351
Lutter, Randall, 161
Macrophages, 295-296
Magnetic resonance imaging (MRI), 15-24
Malaria, 246-250
Manganiello, Michael, 281
Marziali, Andre, 12
Mathews, Katherine J., 13
Mau, Marjorie, 281
MBCD. See Methyl-β-cyclodextrin
McCarty, Maclyn, 108
Medical University of South Carolina, 104
Meller, Amit, 11
Membrane microdomains, 312-316
Mentorship, 73-81, 100, 233-234, 276
Mesangial cell apoptosis, 37-42
Metabolic pathways, 178
Metabolic syndrome, 344-345
Metabolomics, 214-215
Methyl-β-cyclodextrin (MBCD), 322-327
Metzker, Michael L., 11
Mice studies, 135-141, 347-351
Microalbuminuria, 128-133
Microbicides, 343
Microgravity, 82-90
Miller, Steve Z., 2
Mills, Terry L., 105
Minority groups, 232-234
Mishell, Daniel, 224
Molecules, 287-288
Monahan, Brian P., 162
Morehouse School of Medicine, 54
Mount Sinai School of Medicine, 160
MRI. See Magnetic resonance imaging
Mucosal barrier, 318-321
Muller, David, 160
Murine proliferative lupus nephritis, 347-351
Muscle hypertrophy, 135-141
Myers, Martin G., 106
Myocardial innervation imaging, 188
Myocardial metabolism, 434-437
Myocardial perfusion, 184-186
Nabel, Elizabeth G., 106
Nanotechnology, 398-399
National Cancer Institute (NCI), 14, 64, 109, 164, 223, 286, 386, 398-399, 400
National Center for Complementary and Alternative Medicine (NCCAM), 227, 399-400
National Center for Research Resources (NCRR), 7, 111, 55-56, 160, 213-214, 222, 285
National Cholesterol Educational Program Adult Treatment Panel (NCEP-ATP), 31-36, 305-310
National Heart, Lung, and Blood Institute (NHLBI), 106
National Human Genome Research Institute (NHGRI), 10-13, 93-94, 290-291
National Institute of Allergy and Infectious Diseases (NIAID), 94-95, 106, 155-156, 287
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), 161, 439
National Institute of Environmental Health Sciences (NIEHS), 1, 285-286
National Institute of General Medical Sciences (NIGMS), 343
National Institute of Neurological Disorders and Stroke (NINDS), 345-346, 386-387
National Institute of Nursing Research (NINR), 104, 107
National Institute on Aging (NIA), 105, 388
National Institute on Deafness and Other Communication Disorders (NIDCD), 228
National Institutes of Health (NIH)
Alving on, 331-333
archived publications, 58-59, 226-227
base salary policy, 344
clinical research curriculum awards, 123-127
ethics regulation, 57-58, 340
federal budget and, 163
funding of single-nucleotide polymorphism genotyping center, 7-8
General Clinical Research Center, 7
grants and contracts, 94-97, 155-156
in-house researchers, 229
liver disease research plan, 63-64
open access policy, 396
peer review process, 110
predoctoral clinical research training programs, 6, 47-48
principal investigators, 60
proteomics workshop, 61
reauthorization bill, 342
Roadmap for Medical Research, 8-9, 285, 331
science awards, 398
small molecule screening, 287-288
stem cell research funding, 397-398
See alsospecific committees and divisions
National Library of Medicine (NLM), 46-47
National Science Advisory Board for Biosecurity, 337
National Science Foundation (NSF), 344
Natriuretic peptides, 360-382
NCCAM. See National Center for Complementary and Alternative Medicine
NCEP-ATP. See National Cholesterol Educational Program Adult Treatment Panel
NCI. See National Cancer Institute
NCRR. See National Center for Research Resources
Neurotensin, 407-408
Neutrophils, 296
NHGRI. See National Human Genome Research Institute
NHLBI. See National Heart, Lung, and Blood Institute
NIA. See National Institute on Aging
NIAID. See National Institute of Allergy and Infectious Diseases
NIDCD. See National Institute on Deafness and Other Communication Disorders
NIDDK. See National Institute of Diabetes and Digestive and Kidney Diseases
NIEHS. See National Institute of Environmental Health Sciences
NIGMS. See National Institute of General Medical Sciences
NIH. See National Institutes of Health
NINDS. See National Institute of Neurological Disorders and Stroke
NINR. See National Institute of Nursing Research
Nitric oxide, 246-250, 347-351
Nitrilotriacetic acid (NTA), 143-152
NLM. See National Library of Medicine
Nobel Prize in Physiology or Medicine, 5-6
Noe, Bryan, 338, 393
Nonalcoholic steatohepatitis, 353-358
NSF. See National Science Foundation
NTA. See Nitrilotriacetic acid
Nuclear myocardial perfusion, 184-185
Nussbaum, Robert L., 12-13
Nutrition, 404-406
Obesity, 400-401
ODS. See Office of Dietary Supplements
Office for Human Research Protections, 396
Office of Dietary Supplements (ODS), 227
Office of Drug Safety, 394
Open access policy, 396
Orthostatic tolerance, 82-90
Osborn J wave, 434-437
Osteoporosis, 305-310
Oxidative stress
diabetes and, 167-174
in murine proliferative lupus nephritis, 347-351
Pancreatic adenocarcinomas, 361-363
Pancreatic islet cell, 329, 385
Particulate guanylate cyclase, 378-382
Pathophysiology, 176-188
Patient education, 264-266
Payne, Shelley M., 106
Pediatric Heart Network (PHN), 154
Pediatrics. See Children
Pellegrino, Edmund, 337
Peptides, antimicrobial, 294
Peptide YY, 408
Perfusion, 183-186
Peritoneal dialysis, 368
Peroxisome proliferator-activated receptor α L162V, 353-358
Persaud, Deborah, 165
Pfizer Inc., 113-115
PHA. See Phytohemagglutinin
Phagocytosis, 318-321
Pharmaceutical industry, 60-61, 229, 231
Pharmaceutical Research and Manufacturers of America, 60-61
Phenytoin, 164
PHN. See Pediatric Heart Network
Photobleaching, 312-316
Physician Faculty Scholars Program, 273-274
Physician-scientists, 73-81, 114-115, 276
Phytohemagglutinin (PHA), 322-327
Pinn, Vivian W., 280
Plaque, 185-186
Plasmodium, 246-250
Platelets, 329
Pleurodesis, 267-270
Pluripotent stem cells, 226
Polymorphism, 353-358
Pomeroy, Claire, 104-105
Porteus, Matthew, 230
Postmenopause, 305-310
Potassium, 434-437
Pravastatin, 31-36
President's Council on Bioethics, 337
Progestin, 305-310
Proglucagon-derived peptides, 408-409
Protein(s)
extraction, 323
GPI-anchored, 315
green fluorescent, 312-316
kinase, 135-141
small G, 414-422
Proteomics, 61, 93-94, 214-215, 329
Pseudomonas aeruginosa, 319-320
Publications, 226-227
Public health informatics, 287
Pulmonary surfactants, 295
Quake, Stephen R., 11
Rabbit studies, 267-270
Radionuclide-based methods, 176-188
Ramsey, J. Michael, 12
Ras, 315-316
Reactive oxygen species, 246-250
Renin-angiotensin-aldosterone system, 82-90
Research. See Clinical research; Translational research; specific research topics, institutions, and researchers
Reverse transcriptase polymerase chain reaction, 203, 255
Richter, Joel, 282
Robert Wood Johnson Foundation (RWJF), 232-234, 273-274, 287
Ronaghi, Mostafa, 11
RWJF. See Robert Wood Johnson Foundation
Sadee, Wolfgang, 56
Sangamo Biosciences, 230
Sarkin, Richard T., 2
Satcher, David, 54
SBIR. See Small Business Innovation Research
Scarpa, Antonio, 159
Schoolnik, Gary, 106
Schwartz, David A., 1, 285
SCID. See Severe combined immunodeficiency disease
Science Education Partnership Awards, 213-214, 398
Sepsis, 235-243
Serum uric acid (SUA), 116-121
Severe combined immunodeficiency disease (SCID), 230
Sheehan, James, 229
Short bowel syndrome, 402-410
Shumaker, Sally, 228
Signal transduction, 414-422
Silver, George A., 108
Simulated microgravity, 82-90
Single-nucleotide polymorphism, 7-8
Single-photon emission computed tomography (SPECT), 180-182
Siu, Albert L., 105
Skeletal muscle hypertrophy, 135-141
Small Business Innovation Research (SBIR), 95-97
Small Business Technology Transfer (STTR), 95-97
Small molecules, 287-288
Smothers, Barbara A., 104
Society for Neuroscience, 336
SPECT. See Single-photon emission computed tomography
Star, Robert, 222
Statins, 31-36, 322-327, 414-422
Stead, Eugene Anson, 283
Stem cells
California grants for scholars in, 345
cancer and, 272-273
Centers of Excellence, 397-398
embryonic research, 44-45, 109, 289
funding for exploratory centers, 343
human pluripotent, 226
national cord blood bank program, 228
National Stem Cell Bank, 397
research fellowships, 44-45
Stern, David, 280
STTR. See Small Business Technology Transfer
SUA. See Serum uric acid
Sung, Nancy S., 217-220
Surfactants, 235-243, 295
Syndrome X. See Metabolic syndrome
TACC. See Tri-Service Aids Clinical Consortium
Temple University School of Medicine, 282
Tetracycline, 267-270
Thal, Leon, 105
Therapeutic infusion, 371-375
Thioredoxin, 167-174
Thrombicidins, 295
Tinetti, Mary E., 105
TNF-α. See Tumor necrosis factor-α
Translational informatics, 46-47
Translational research, 192-198, 271-272, 275, 288, 386-387, 397-398, 438-439
Trefoil peptides, 402-410
Tri-Service Aids Clinical Consortium (TACC), 94-95
Tumor angiogenesis, 340-341
Tumor necrosis factor-α, 299
Type 1 diabetes, 62-63
University of Alabama, 229-230, 338, 392-393
University of California, Davis, 104-105
University of Cincinnati College of Medicine, 280
University of Maryland, 338
University of Pennsylvania, 61-62
University of South Alabama, 159, 389
University of Southern California School of Pharmacy, 393
University of Texas Southwestern Medical School, 99, 279
University of Wisconsin, 54, 393
Unwin, David “Hal,” 284
Uric acid, 116-121
Vaccine, HIV, 401
Vaitukaitis, Judith, 160
Vanderveen, Randall L. “Pete,” 393
Van Essen, David, 336
Vascular endothelial growth factor, 253-262
Vaughan, Darracott, 334
Ventricular myocytes, 415
Ventricular remodeling, 178
von Eschenbach, Andrew, 395
Wakil, Salih J., 281
Wald, Ellen, 393-394
Waldman, Scott, 335
Washington University (St. Louis), 223-224
Wayne State University School of Medicine, 279, 389
Weill Medical College (Cornell University), 334
WHO. See World Health Organization
Williams, John, 11
Williams, Peter, 11
Wilson, Donald, 338
Wilson, James, 109-110
Wilson, Peter, 104
Women
hormone replacement therapy, 305-310
in medical research, 228
microbicides for, 343
Women's Health Initiative, 305-310
World Health Organization (WHO), 31-36
X-ray absorptiometry, 15-24
Yoshikawa, Thomas, 394
Ziff, Morris, 339
Zorilla, Carmen, 280