Indexes ======= ## AUTHOR INDEX Abbud, Eliyya, 434 Abraham, Soman N., 318 Aleveritis, Ellie, 305 Atalay, Habip, 267 Athyros, Vasilios G., 116 Aytekin, Faruk Onder, 267 Baase, Catherine, 67 Bairaktari, Eleni, 116 Bakken, Lori L., 123 Barilli, Angela Luciana, 26 Bayless, Kayla J., 414 Beharry, Kay D.A., 253 Berenji, Kambeez, 414 Bertoni, Roberto, 26 Bir, Ferda, 267 Blazhev, Alexander, 128 Bonow, Robert, 67 Bozdayi, Abdurrahman Mithat, 353 Bozkaya, Hakan, 353 Britigan, Bradley E., 143 Brunson, Charlie E., 434 Buchman, Alan L., 402 Burnett, John C., Jr, 378 Califf, Robert, 67 Campbell, Adam G., 201 Cariolou, Marios, 116 Cataliotti, Alessandro, 378 Catanese, Veronica, 67 Chen, Dali, 15 Christova, Petkama, 128 Cinar, Kubilay, 353 Cisler, Jason J., 402 Clancy, Carolyn M., 65 Cohen, Richard J., 82 Coiro, Vittorio, 26 Colleran, Kathleen M., 264 Cowen, Daniel S., 37 Crowley, William F., Jr, 425 Davis, George E., 414 de Bold, Adolfo J., 371 de Bold, Mercedes L. Kuroski, 371 Dekov, Dancho, 128 Delafontaine, Patrick, 135 Delsignore, Roberto, 26 Desai, Bijal D., 37 Dinges, Warren L., 15 Di Secli, Clelia, 26 Dobs, Adrian, 67 Dorovski, Plamen, 128 Dowdy, David, 192 Duann, Pu, 37 Duncan, Matthew J., 318 Elisaf, Moses S., 116 Erden, Esra, 353 Ergül, Ayça Arslan, 353 Ferrari, Carlo, 26 Feussner, John, 67 Finardi, Lorenzo, 26 Forrest, Kathy, 322 Frangos, John A., 246 Gallin, Elaine K., 73 Ganotakis, Manolis, 116 Garg, Abhimanyu, 15 Genel, Myron, 67 Glaser, John, 425 Godard, Michael, 135 Goebel, Jens, 322 Gramaglia, Irene, 246 Grenon, S. Marlene, 82 Guha, Bhuvana, 305 Guidot, David M., 235 Hart, C. Michael, 235 Hill, Joseph A., 414 Ho, Teh-Yuan, 37 Hörl, Walter H., 366 Hurwitz, Shelley, 82 Idilman, Ramazan, 353 Intaglietta, Marcos, 246 Ismail, Hassan M., 31, 305 Johnson, Stephen B., 192 Jordanova-Laleva, Pavlima, 128 Jotti, Gloria Saccani, 26 Kapoian, Toros, 37 Kaya, Seyda Ors, 267 Kenworthy, Anne K., 312 Keogh, Diane, 425 Kim, Christine, 82 Koytak, Elif Sare, 353 Kupersmith, Joel, 67 La Gioia, Daniele, 26 LeBlancq, Sylvie M., 73 Li, Guojie, 318 Li, Yangxin, 135 Lianos, Elias A., 37 Liberopoulos, Evagelos N., 116 Lichtenstein, Michael, 123 Logan, Barbara, 322 Markov, Angel K., 434 Metcalf, Jordan P., 292 Michelena, Hector I., 176 Mieczkowski, Alexandra, 322 Miltiadous, George A., 116 Minelli, Roberta, 26 Modanlou, Houchang D., 253 Nazir, Shoab A., 292 Nicoloff, George, 128 Njoku, Chinedu J., 347 Noiri, Eisei, 167 Nolan, Bridgid, 414 Oates, Jim C., 347 Olakanmi, Oyebode, 143 Olive, Kenneth, 305 Olson, Darin E., 201 Önder, Oğuz, 353 Onem, Gokhan, 267 Osman, Khidir, 434 Panja, Srinivas, 264 Patrick, Kennerly S., 347 Paveglio, Sara A., 201 Payne, Philip R.O., 192 Peterson, Dolores M., 15 Petrova, Chaika, 128 Pfortmiller, Deborah, 31 Porter, Marty H., 201 Ramsdell, Craig D., 82 Reame, Nancy, 67 Reece, E. Albert, 67 Richardson, Kenneth E., 414 Richmond, Scott R., 135 Rosenthal, Nadia, 135 Roszman, Thomas L., 322 Rothermel, Beverly A., 414 Ruiz, Philip, Jr, 347 Saçar, Mustafa, 267 Salahudeen, Abdulla K., 360 Sherwood, Louis, 67 Sheynberg, Natalie, 82 Simmons, Christina, 31 Skelton, Thomas N., 434 Slavkin, Harold, 67 Sloan, Susan, 305 Slutsky, Jean R., 65 Snell, Peter G., 15 Sobolewski, Peter, 246 Song, Yao-Hua, 135 Starr, Brian, 264 Starren, Justin B., 192 Stokes, John B., 143 Stubbs, Connie, 425 Sung, Nancy, 67 Tambunting, Francis, 253 Tannous, Paul, 414 Thulé, Peter M., 201 Tilson, Hugh, 67, 192 Tsukahara, Hirokazu, 167 Turisco, Fran, 425 Uzunalimoglu, Özden, 353 Valli, Maria Antonietta, 26 VanDecker, William A., 176 van der Heyde, Henri C., 246 Verdi, Hasibe, 353 Vesely, David L., 360 Waltzman, Joshua, 253 Weatherall, Paul T., 15 Williams, Gordon H., 82 Wills-Karp, Marsha, 322 Xiao, Xinshu, 82 Yurdaydin, Cihan, 353 Zaas, David, 318 Zhang, Jin-an, 201 ## SUBJECT INDEX AAM. *See* American Academy of Microbiology AAMC. *See* Association of American Medical Colleges AAPS. *See* American Association of Pharmaceutical Scientists ABCR. *See* Advisory Board for Clinical Research Abraham, Edward, 392 Absorptiometry, 15-24 Academic health centers, 331-333, 425-433 ACRWH. *See* Advisory Committee on Research on Women's Health Acute coronary syndromes, 178 Acute lung injury, 235-243 Acute myocardial infarction, 371-375 Acute renal failure, 366-369 Acute respiratory distress syndrome, 235-243 Ad. *See* Adenovirus Adashi, Eli Y., 55 Adenocarcinomas, 361-363 Adenosine A3 receptor, 37-42 Adenosine triphosphate, 434-437 Adenovirus (Ad) innate immune response to, 292-300 insulin gene therapy, 201-210 Advanced glycation end products, 167-174 Advisory Board for Clinical Research (ABCR), 229 Advisory Committee on Research on Women's Health (ACRWH), 228, 280 AEAbs. *See* Antielastin antibodies AFMR. *See* American Federation for Medical Research Ahlport, Kathryn N., 217-220 AIDS. *See* HIV (human immunodeficiency virus) ALA. *See* American Lung Association Albert Lasker Award for Basic Medical Research, 4-5 Albert Lasker Award for Clinical Medical Research, 4-5 Alcohol abuse, 235-243 Alcohol biomarkers, 214-216 Aldosterone, 378-382 Alternative medicine, 399-400 Alveolar epithelium, 235-243, 319-320 Alving, Barbara, 222, 331-333 Alzheimer's disease, 45-46, 388 American Academy of Microbiology (AAM), 111-112 American Association for Cancer Research, 386 American Association of Pharmaceutical Scientists (AAPS), 56 American Diabetes Association, 31-36 American Federation for Medical Research (AFMR), 312, 360, 391 American Lung Association (ALA), 273 Amgen, Inc., 386 Angiogenesis, 92, 340-341 Angiogram, 179-180 Anthropometry, 15-24 Antielastin antibodies (AEAbs), 128-133 Antimicrobial peptides, 294 Antman, Karen H., 107 Apolipoprotein E, 116-121 Apoptosis, mesangial cell, 37-42 Archived publications, 58, 226-227 Arnold, Janice Lee, 161 AS. *See* Atorvastatin Association of American Medical Colleges (AAMC), 2, 7, 13-14, 59, 103 Atherosclerosis, 31-36, 177-178 Atorvastatin (AS), 31-36, 322-327 Atrial natriuretic peptides, 360-382 Axel, Richard, 5-6 Bacterial mucosal barrier, 318-321 Baker, Nicole Johnson, 281 Battey, James, 228-229 Benner, Steven A., 11, 12 Beta cells, 213 Bilirubin, 171-172 Biodefense, 155-156, 216-217, 287 Biomedical informatics, 192-198 Biomedical institutes, 61-62 Biomedical research, 123-127 Bladder epithelial cells, 319 Blood flow, 179 Bloom, Joseph D., 1 Body fat distribution, 15-24 Bond, Enriqueta C., 217-220 Boston University School of Medicine, 107 Botanical products, 227 Boyd-Ford, Valda, 281 Brain natriuretic peptide, 371-382 Breast adenocarcinoma, 363 Bristol-Myers Squibb Awards, 163, 281, 386 Bristol-Myers Squibb Oncology Fellowship in Clinical Cancer Research, 386 Bronchopulmonary dysplasia, 253-262 Brown-Friday, Janet O., 161 Brown University, 55 Buck, Linda, 5-6 Burroughs Wellcome Fund, 217-221 CAD. *See* Coronary artery disease Cain, Joanna, 228 Calcineurin, 414-422 California Institute for Regenerative Medicine, 223, 345 Cancer biology program, 14 clinical trials, 286 consumer liaison group, 64 nanotechnology in, 398-399 natriuretic peptides and, 360-363 obesity and, 400-401 research, 163, 398-399 stem cells and, 272-273 Carbamazepine, 164 Cardiac fibrosis, 380-382 Cardiac hypertrophy, 414-422 Cardioendocrine system, 82-90 Cardiomyocytes, 415 Cardiovascular cell therapy, 385 Cardiovascular disease, 373-374 Cardiovascular system, 82-90 Cathelecidins, 294-295 Caveolae, 315, 318-321 CDC. *See* Centers for Disease Control and Prevention Center for Scientific Review, 159 Centers for Disease Control and Prevention (CDC), 95-97 Centers of Research Translation (CORT), 271-272 Chambon, Pierre, 4-5 Chapman, John E., 2 Charles E. Culpeper Scholarships in Medical Science, 217 C-HC. *See* Chronic hepatitis C Children diabetic, 128-133 Pediatric Heart Network, 154 Chinese medicine, 399, 400 Cholesterol, 31-36, 316 Chronic hepatitis C (C-HC), 26-29 Cicero, Theodore J., 223-224 CIF. *See* Complement inhibition factor CIST. *See* Clinical Investigators Student Training (CIST) Forum Clark, Christina, 281 Clark, Luther, 280 Clinical and Translational Science Awards (CTSAs), 438-439 Clinical Investigators Student Training (CIST) Forum, 3-4 Clinical research Alving on, 332 Crowley on, 51-53 fellowships, 73-81, 290 information technology and, 192-198, 425-433 loan repayment program, 385 new General Clinical Research Center, 7 predoctorial training programs, 6, 47-48 support for, 288 task force on, 7 See alsospecific institutions, researchers, and fields of research Clinical research curriculum awards (CRCA), 123-127 Cohen, Jordan J., 103 Collins, Scott D., 12 Columbia University, 282 Complementary medicine, 399-400 Complement inhibition factor (CIF), 128-133 Coney, Ponjola, 280 Conflict of interest, 57-58, 112, 228-229 Congestive heart failure, 371-375 COPR. *See* Council of Public Representatives Cord blood stem cell bank, 228 Coronary angiogram, 179-180 Coronary artery disease (CAD), 31-36, 176-188, 305-310 Coronary blood flow, 179 Corr, Peter B., 113-115 CORT. *See* Centers of Research Translation Costa, Gina L., 11 Council of Public Representatives (COPR), 281 Council on Competitiveness, 111 Crawford, Lester, 334 CRCA. *See* Clinical research curriculum awards Crook, Errol, 159, 389-391 Crowley, William, 49-53 CTSAs. *See* Clinical and Translational Science Awards Cyclic guanosine monophosphate, 360-363 Cytokines, 297 Dallas Heart Study, 101-102 Dal Pan, Gerald, 394 Davis, Ronald W., 12 DDCF. *See* Doris Duke Charitable Foundation Defensins, 294 Dendritic cells, 296 DEXA. *See* Dual-energy x-ray absorptiometry Diabetes beta cell regeneration for, 213 in children, 128-133 glycemic control, 264-266 hyperlipidemia and, 31-36 L162V polymorphism and, 355 oxidative stress and, 167-174 prognosis, 185 type 1, 62-63, 92 Diclofenac sodium, 267-270 Dietary supplements, 227 DNA sequencing, 10-12 DNA synthesis, 360-363 Doris Duke Charitable Foundation (DDCF), 275-278 Doris Duke Clinical Research Fellowship Program, 73-81 Drew University, 394 Drexel University, 1 Drug safety, 61-62 Dual-energy x-ray absorptiometry (DEXA), 15-24 Dunaif, Andrea, 280 East Tennessee State University, 305-310 Eckhert, N. Lynn, 2 Ejection fraction, 178 Electrocardiogram, 434-437 Embryonic stem cells. *See* Stem cells Endocrinology, 49 Enzyme-linked immunosorbent assay, 167-174 Epidermal growth factor, 402-410 Epilepsy, 164 Epithelial cells, 296-297, 318-321 *Escherichia coli,* 319 Estrogen, 305-310 Ethanol, 239-240 Ethics, 57-58, 340 Evans, Ronald M., 4, 5 Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 31-36 Farrell, Philip M., 54 Fasting glucose, 31-36 Fatty acids, 167-174, 187-188 Fatty liver, 353-358 FDA. *See* Food and Drug Administration FIC. *See* Fogarty International Center Fischbach, Gerald, 282 Flack, John, 279 Flier, Jeffrey Scott, 161 Flow cytometry, 323 Fluorescence, 312-316 Fogarty International Center (FIC), 290, 396-397 Food and Drug Administration (FDA), 60, 95-97, 161, 290, 334, 395 Ford, Daniel, 335 Free antielastin antibodies, 128-133 Fugh-Berman, Adriane, 231 Gallin, Elaine, 275-278 Gallium, 143-152 Gastrin, 402-410 Gavin, James R. III, 232-234 GCRCs. *See* General clinical research centers GD. *See* Graves' disease General clinical research centers (GCRCs), 332-333 Gene(s) database, 111-112, 164 insulin therapy, 201-210 predictive value, 164 studies, 62-63, 163 therapy, 109-110, 230 Genomes, 10-12, 93-94, 111-112, 166 Genomics, 93-94, 214-215 Genotyping, 7-8 Ghostwriting, 231 Gilman, Alfred, 279 Global health, 290, 396-397 Global Registry of Acute Coronary Events, 31-36 Glucagon-like peptide, 402-410 Glucose impaired fasting, 31-36 uptake, 201-210 Glutathione, 235-243 Glycemic control, 264-266 Glycogen, 201-210 Glycogenolysis, 206 Glycosylphosphatidylinositol-anchored proteins, 315 GM-1 marker, 322-327 Goldman Philanthropic Partnerships, 217 Graves' disease (GD), 26-29 Gray, Paulette, 223 Green fluorescent protein, 312-316 Greengard, Paul, 105 Greenwalt, Tibor J., 283 Grieder, Franziska, 55-56 Growth factors, 402-410 Guanosine triphosphatase, 414-422 Guttmacher, Alan E., 12-13 Gynecologic Cancer Foundation, 386 Hall, Zack, 223 Harold Amos Medical Faculty Development Program, 232-234 Harvard School of Public Health, 56 Health and Human Services (HHS), 10, 59-60, 288 Health care effectiveness, 65-71 information network, 342-343 report on inefficiencies, 341 Health information technology, 10 Health insurance, 67-71 Health Insurance Portability and Accountability Act (HIPAA), 285 Heart failure, 378-382, 401 natriuretic peptides and, 371-382 Pediatric Heart Network, 154 Heart and Estrogen/Progestin Replacement Study, 305-310 Heat-related illnesses, 401 Hellmann, David, 336 Hematopoietic progenitor stem cells, 228 Hemoglobin, 246-250 Henrich, William L., 161 Hepatic insulin gene therapy, 201-210 Hepatitis C chronic, 26-29 virus-related liver steatosis, 353-358 Hepatocyte growth factor, 409 Herbal supplements, 227 Herbert W. Nickens Awards, 13-14 HHMI. *See* Howard Hughes Medical Institute HHS. *See* Health and Human Services HIPAA. *See* Health Insurance Portability and Accountability Act HIV (human immunodeficiency virus) regional body fat distribution in, 15-24 Tri-Service AIDS Clinical Consortium, 94-95 vaccine, 401 Hobbs, Helen, 99-102 Hormone replacement therapy (HRT), 305-310 Host cells, 201-210 Howard Hughes Medical Institute (HHMI), 112, 165, 230 HRT. *See* Hormone replacement therapy Human Genome Project, 50 Human immunodeficiency virus. *See* HIV Human pluripotent stem cells, 226 Hyperlipidemia, 31-36, 305-310 Hypertrophy cardiac, 414-422 skeletal muscle, 135-141 Hypothermia, 434-437 IGF-I. *See* Insulin-like growth factor I IL-1. *See* Interleukin-1 IL-2. *See* Interleukin-2 IL-6. *See* Interleukin-6 IL-8. *See* Interleukin-8 IL-12. *See* Interleukin-12 Immune responses, 292-300 Immunoblotting, 324 Immunoprecipitation, 323-324 Impaired fasting glucose, 31-36 Imperiale, Michael, 337 Information technology, 10, 46-47, 192-198, 425-433 Innate immune response, 292-300 Innovation, 111 Insel, Richard, 106 Insel, Thomas, 229 Institute of Medicine (IOM), 12-13, 228 Institutional review boards (IRBs), 227 Insulin-like growth factor I (IGF-I), 135-141 Interferons, 26-29, 299 Interleukin-1, 297 Interleukin-2, 322-327 Interleukin-6, 298 Interleukin-8, 298 Interleukin-12, 298-299 Internal medicine, 288 IOM. *See* Institute of Medicine IRBs. *See* Institutional review boards Iron, 143-152 Ischemic cascade, 178-179 Ischemic heart disease, 176-188 Islet cells, 111, 329, 385 Isoprostanes, 347-351 JDRF. See Juvenile Diabetes Research Foundation Jefferson Medical College, 335 Jensen, Elwood V., 4, 5 Johns Hopkins University School of Medicine, 335-336, 392 Jovanovich, Stevan B., 11 Ju, Jingyue, 11 Juvenile Diabetes Research Foundation (JDRF), 92, 329 Kast, Linda, 280 Keck School of Medicine, 224 Kelman, Charles, 4 Kerr, Mary E., 107 Kidney disease, 62-63, 366-369 Klag, Michael, 392 Knudson, Alfred G., Jr, 163-164 Koh, Howard, 56 Korsmeyer, Stanley, 225 Lateral diffusion, 312-316 LDL. *See* Low-density lipoprotein Lee, James Weifu, 12 Left ventricular function, 186 Linares-Orama, Nicolas, 281 Lindquist, Cynthia, 281 Lindsay, Stuart, 12 Lipid abnormalities, 355 Lipid metabolism, 116-121 Lipid peroxide, 167-174 Lipid rafts, 312-316, 318-327 Lipids, 31-36 Lipodystrophy, 15-24 Liver disease, 63-64 insulin gene therapy, 201-210 steatosis, 353-358 Lohman, Kenton, 11 L162V polymorphism, 355 Low-density lipoprotein (LDL), 31-36 Lung disease, 253-262, 273 Lung injury, 235-243 Lupus nephritis, 347-351 Lutter, Randall, 161 Macrophages, 295-296 Magnetic resonance imaging (MRI), 15-24 Malaria, 246-250 Manganiello, Michael, 281 Marziali, Andre, 12 Mathews, Katherine J., 13 Mau, Marjorie, 281 MBCD. *See* Methyl-β-cyclodextrin McCarty, Maclyn, 108 Medical University of South Carolina, 104 Meller, Amit, 11 Membrane microdomains, 312-316 Mentorship, 73-81, 100, 233-234, 276 Mesangial cell apoptosis, 37-42 Metabolic pathways, 178 Metabolic syndrome, 344-345 Metabolomics, 214-215 Methyl-β-cyclodextrin (MBCD), 322-327 Metzker, Michael L., 11 Mice studies, 135-141, 347-351 Microalbuminuria, 128-133 Microbicides, 343 Microgravity, 82-90 Miller, Steve Z., 2 Mills, Terry L., 105 Minority groups, 232-234 Mishell, Daniel, 224 Molecules, 287-288 Monahan, Brian P., 162 Morehouse School of Medicine, 54 Mount Sinai School of Medicine, 160 MRI. *See* Magnetic resonance imaging Mucosal barrier, 318-321 Muller, David, 160 Murine proliferative lupus nephritis, 347-351 Muscle hypertrophy, 135-141 Myers, Martin G., 106 Myocardial innervation imaging, 188 Myocardial metabolism, 434-437 Myocardial perfusion, 184-186 Nabel, Elizabeth G., 106 Nanotechnology, 398-399 National Cancer Institute (NCI), 14, 64, 109, 164, 223, 286, 386, 398-399, 400 National Center for Complementary and Alternative Medicine (NCCAM), 227, 399-400 National Center for Research Resources (NCRR), 7, 111, 55-56, 160, 213-214, 222, 285 National Cholesterol Educational Program Adult Treatment Panel (NCEP-ATP), 31-36, 305-310 National Heart, Lung, and Blood Institute (NHLBI), 106 National Human Genome Research Institute (NHGRI), 10-13, 93-94, 290-291 National Institute of Allergy and Infectious Diseases (NIAID), 94-95, 106, 155-156, 287 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), 161, 439 National Institute of Environmental Health Sciences (NIEHS), 1, 285-286 National Institute of General Medical Sciences (NIGMS), 343 National Institute of Neurological Disorders and Stroke (NINDS), 345-346, 386-387 National Institute of Nursing Research (NINR), 104, 107 National Institute on Aging (NIA), 105, 388 National Institute on Deafness and Other Communication Disorders (NIDCD), 228 National Institutes of Health (NIH) Alving on, 331-333 archived publications, 58-59, 226-227 base salary policy, 344 clinical research curriculum awards, 123-127 ethics regulation, 57-58, 340 federal budget and, 163 funding of single-nucleotide polymorphism genotyping center, 7-8 General Clinical Research Center, 7 grants and contracts, 94-97, 155-156 in-house researchers, 229 liver disease research plan, 63-64 open access policy, 396 peer review process, 110 predoctoral clinical research training programs, 6, 47-48 principal investigators, 60 proteomics workshop, 61 reauthorization bill, 342 Roadmap for Medical Research, 8-9, 285, 331 science awards, 398 small molecule screening, 287-288 stem cell research funding, 397-398 See alsospecific committees and divisions National Library of Medicine (NLM), 46-47 National Science Advisory Board for Biosecurity, 337 National Science Foundation (NSF), 344 Natriuretic peptides, 360-382 NCCAM. *See* National Center for Complementary and Alternative Medicine NCEP-ATP. *See* National Cholesterol Educational Program Adult Treatment Panel NCI. *See* National Cancer Institute NCRR. *See* National Center for Research Resources Neurotensin, 407-408 Neutrophils, 296 NHGRI. *See* National Human Genome Research Institute NHLBI. *See* National Heart, Lung, and Blood Institute NIA. *See* National Institute on Aging NIAID. *See* National Institute of Allergy and Infectious Diseases NIDCD. *See* National Institute on Deafness and Other Communication Disorders NIDDK. *See* National Institute of Diabetes and Digestive and Kidney Diseases NIEHS. *See* National Institute of Environmental Health Sciences NIGMS. *See* National Institute of General Medical Sciences NIH. *See* National Institutes of Health NINDS. *See* National Institute of Neurological Disorders and Stroke NINR. *See* National Institute of Nursing Research Nitric oxide, 246-250, 347-351 Nitrilotriacetic acid (NTA), 143-152 NLM. *See* National Library of Medicine Nobel Prize in Physiology or Medicine, 5-6 Noe, Bryan, 338, 393 Nonalcoholic steatohepatitis, 353-358 NSF. *See* National Science Foundation NTA. *See* Nitrilotriacetic acid Nuclear myocardial perfusion, 184-185 Nussbaum, Robert L., 12-13 Nutrition, 404-406 Obesity, 400-401 ODS. *See* Office of Dietary Supplements Office for Human Research Protections, 396 Office of Dietary Supplements (ODS), 227 Office of Drug Safety, 394 Open access policy, 396 Orthostatic tolerance, 82-90 Osborn J wave, 434-437 Osteoporosis, 305-310 Oxidative stress diabetes and, 167-174 in murine proliferative lupus nephritis, 347-351 Pancreatic adenocarcinomas, 361-363 Pancreatic islet cell, 329, 385 Particulate guanylate cyclase, 378-382 Pathophysiology, 176-188 Patient education, 264-266 Payne, Shelley M., 106 Pediatric Heart Network (PHN), 154 Pediatrics. *See* Children Pellegrino, Edmund, 337 Peptides, antimicrobial, 294 Peptide YY, 408 Perfusion, 183-186 Peritoneal dialysis, 368 Peroxisome proliferator-activated receptor α L162V, 353-358 Persaud, Deborah, 165 Pfizer Inc., 113-115 PHA. *See* Phytohemagglutinin Phagocytosis, 318-321 Pharmaceutical industry, 60-61, 229, 231 Pharmaceutical Research and Manufacturers of America, 60-61 Phenytoin, 164 PHN. *See* Pediatric Heart Network Photobleaching, 312-316 Physician Faculty Scholars Program, 273-274 Physician-scientists, 73-81, 114-115, 276 Phytohemagglutinin (PHA), 322-327 Pinn, Vivian W., 280 Plaque, 185-186 *Plasmodium,* 246-250 Platelets, 329 Pleurodesis, 267-270 Pluripotent stem cells, 226 Polymorphism, 353-358 Pomeroy, Claire, 104-105 Porteus, Matthew, 230 Postmenopause, 305-310 Potassium, 434-437 Pravastatin, 31-36 President's Council on Bioethics, 337 Progestin, 305-310 Proglucagon-derived peptides, 408-409 Protein(s) extraction, 323 GPI-anchored, 315 green fluorescent, 312-316 kinase, 135-141 small G, 414-422 Proteomics, 61, 93-94, 214-215, 329 *Pseudomonas aeruginosa,* 319-320 Publications, 226-227 Public health informatics, 287 Pulmonary surfactants, 295 Quake, Stephen R., 11 Rabbit studies, 267-270 Radionuclide-based methods, 176-188 Ramsey, J. Michael, 12 Ras, 315-316 Reactive oxygen species, 246-250 Renin-angiotensin-aldosterone system, 82-90 Research. *See* Clinical research; Translational research; *specific research topics, institutions, and researchers* Reverse transcriptase polymerase chain reaction, 203, 255 Richter, Joel, 282 Robert Wood Johnson Foundation (RWJF), 232-234, 273-274, 287 Ronaghi, Mostafa, 11 RWJF. *See* Robert Wood Johnson Foundation Sadee, Wolfgang, 56 Sangamo Biosciences, 230 Sarkin, Richard T., 2 Satcher, David, 54 SBIR. *See* Small Business Innovation Research Scarpa, Antonio, 159 Schoolnik, Gary, 106 Schwartz, David A., 1, 285 SCID. *See* Severe combined immunodeficiency disease Science Education Partnership Awards, 213-214, 398 Sepsis, 235-243 Serum uric acid (SUA), 116-121 Severe combined immunodeficiency disease (SCID), 230 Sheehan, James, 229 Short bowel syndrome, 402-410 Shumaker, Sally, 228 Signal transduction, 414-422 Silver, George A., 108 Simulated microgravity, 82-90 Single-nucleotide polymorphism, 7-8 Single-photon emission computed tomography (SPECT), 180-182 Siu, Albert L., 105 Skeletal muscle hypertrophy, 135-141 Small Business Innovation Research (SBIR), 95-97 Small Business Technology Transfer (STTR), 95-97 Small molecules, 287-288 Smothers, Barbara A., 104 Society for Neuroscience, 336 SPECT. *See* Single-photon emission computed tomography Star, Robert, 222 Statins, 31-36, 322-327, 414-422 Stead, Eugene Anson, 283 Stem cells California grants for scholars in, 345 cancer and, 272-273 Centers of Excellence, 397-398 embryonic research, 44-45, 109, 289 funding for exploratory centers, 343 human pluripotent, 226 national cord blood bank program, 228 National Stem Cell Bank, 397 research fellowships, 44-45 Stern, David, 280 STTR. *See* Small Business Technology Transfer SUA. *See* Serum uric acid Sung, Nancy S., 217-220 Surfactants, 235-243, 295 Syndrome X. *See* Metabolic syndrome TACC. *See* Tri-Service Aids Clinical Consortium Temple University School of Medicine, 282 Tetracycline, 267-270 Thal, Leon, 105 Therapeutic infusion, 371-375 Thioredoxin, 167-174 Thrombicidins, 295 Tinetti, Mary E., 105 TNF-α. *See* Tumor necrosis factor-α Translational informatics, 46-47 Translational research, 192-198, 271-272, 275, 288, 386-387, 397-398, 438-439 Trefoil peptides, 402-410 Tri-Service Aids Clinical Consortium (TACC), 94-95 Tumor angiogenesis, 340-341 Tumor necrosis factor-α, 299 Type 1 diabetes, 62-63 University of Alabama, 229-230, 338, 392-393 University of California, Davis, 104-105 University of Cincinnati College of Medicine, 280 University of Maryland, 338 University of Pennsylvania, 61-62 University of South Alabama, 159, 389 University of Southern California School of Pharmacy, 393 University of Texas Southwestern Medical School, 99, 279 University of Wisconsin, 54, 393 Unwin, David “Hal,” 284 Uric acid, 116-121 Vaccine, HIV, 401 Vaitukaitis, Judith, 160 Vanderveen, Randall L. “Pete,” 393 Van Essen, David, 336 Vascular endothelial growth factor, 253-262 Vaughan, Darracott, 334 Ventricular myocytes, 415 Ventricular remodeling, 178 von Eschenbach, Andrew, 395 Wakil, Salih J., 281 Wald, Ellen, 393-394 Waldman, Scott, 335 Washington University (St. Louis), 223-224 Wayne State University School of Medicine, 279, 389 Weill Medical College (Cornell University), 334 WHO. *See* World Health Organization Williams, John, 11 Williams, Peter, 11 Wilson, Donald, 338 Wilson, James, 109-110 Wilson, Peter, 104 Women hormone replacement therapy, 305-310 in medical research, 228 microbicides for, 343 Women's Health Initiative, 305-310 World Health Organization (WHO), 31-36 X-ray absorptiometry, 15-24 Yoshikawa, Thomas, 394 Ziff, Morris, 339 Zorilla, Carmen, 280