Article Figures & Data
Figures
- Figure 1
Diabetes mellitus (DM) rate with normal triglyceride levels after 7.6 years of follow-up.
- Figure 2
Impaired fasting glucose (IFG) rate with normal triglyceride levels after 7.6 years of follow-up.
Tables
- Table 1
Characteristics of 5085 participants without diabetes attending a health screening center
Men Women Total n=3746 n=1339 N=5085 p Value Age (years), mean±SD 42.6±8.9 43.5±9.3 42.8±9 0.001 Follow-up (year), mean±SD 7.7±2.0 7.3±1.9 7.6±2.0 <0.001 BMI (kg/m2), mean±SD 26.8±3.7 24.8±4.4 26.3±3.96 <0.001 Impaired fasting glucose, n (%) 764 (20.4%) 157 (11.7%) 921 (18.1%) <0.001 Hypertriglyceridemia, n (%) 1181 (31.5%) 182 (13.6%) 1363 (27%) <0.001 Hypertension, n (%) 168 (4.5%) 41 (3.1% ) 209 (4.1%) 0.025 Family history of diabetes, n (%) 795 (21.3%) 300 (22.6%) 1095 (21.6%) 0.33 HDL cholesterol (mg/dL), mean±SD 45.8±9.6 60±13.7 49.5±12.5 <0.001 LDL cholesterol (mg/dL) mean±SD 127.3±0.4 119.1±30.7 124.7±30.7 <0.001 BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
- Table 2
Baseline characteristics of participants diagnosed with DM by the end of the study
DM No DM n=170 n=4915 p Value Age (year), mean±SD 48.3±8.7 42.6±8.9 <0.001 Men, n (%) 139 (82%) 3607 (73%) 0.02 BMI (kg/m2), mean±SD 29.1±4.3 26.2±3.9 <0.001 Impaired fasting glucose, n (%) 130 (76%) 791 (16%) <0.001 Triglycerides (mg/dL), mean±SD 172.6±89.7 123.2±70.9 <0.001 Hypertriglyceridemia, n (%) 83 (49%) 1280 (26%) <0.001 Hypertension, n (%) 21 (12.4%) 188 (4%) <0.001 Family history of DM, n (%) 75 (44%) 1020 (21%) <0.001 HDL cholesterol (mg/dL), mean±SD 44.3±9.3 49.7±12.6 <0.001 LDL cholesterol (mg/dL), mean±SD 129.9±31.4 124.6±30.7 0.048 BMI, body mass index; DM, diabetes mellitus; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
- Table 3
Results of stepwise logistic regression analysis of risk of diabetes mellitus in normoglycemic participants for all triglyceride levels
Variable/step number OR 95% CI p Value Triglycerides/10 1.04 1.02 to 1.07 <0.001 Family history 3.19 1.69 to 6.03 <0.001 BMI 1.11 1.04 to 1.19 0.003 Age/10 1.45 1.02 to 2.06 0.044 AUC, area under the curve=0.77.
BMI, body mass index.
- Table 4
Results of stepwise logistic regression for analysis of risk of diabetes mellitus in participants with impaired fasting glucose for all triglyceride levels
Variable/step number OR 95% CI p Value Tg/HDL ratio 1.19 1.70 to 3.77 <0.001 Family history 2.56 1.02 to 1.07 <0.001 Age/10 1.59 1.24 to 1.93 <0.001 BMI 1.06 1.02 to 1.12 0.017 AUC, area under the curve=0.70.
BMI, body mass index; HDL, high-density lipoprotein.
- Table 5
Baseline characteristics of participants with IFG by the end of the study, excluding those who had initial IFG and those who developed DM
IFG No IFG n=998 n=3126 p Value Age (years), mean±SD 44.7±8.8 41.1±8.6 <0.001 Men, n (%) 800 (80.2%) 2153 (68.9%) <0.001 BMI (kg/m2), mean±SD 27.1±3.8 25.5±3.7 <0.001 Triglycerides (mg/dL), mean±SD 134.8±80.4 115±66.5 <0.001 Hypertriglyceridemia, n (%) 321 (32.2 %) 672 (21.5%) <0.001 Hypertension, n (%) 52 (5.2%) 73 (2.3%) <0.001 Family history of DM, n (%) 244 (24.5%) 581 (18.7%) <0.001 HDL cholesterol (mg/dL), mean±SD 47.9±11.4 50.7±13.1 <0.001 LDL cholesterol (mg/dL), mean±SD 127.6±30.7 122.1±30.4 <0.001 BMI, body mass index; DM, diabetes mellitus; HDL, high-density lipoprotein; IFG, impaired fasting glucose; LDL, low-density lipoprotein.
- Table 6
Results of stepwise logistic regression for analysis of risk of impaired fasting glucose in normoglycemic participants for all triglyceride levels excluding Tg/HDL ratio
Variable/step no. OR 95% CI p Value Gender (M) 1.69 1.37 to 2 <0.001 Age/10 1.57 1.44 to 1.70 <0.001 Family history 1.45 1.21 to 1.72 <0.001 BMI 1.08 1.06 to 1.10 <0.001 Triglyceride/10 1.02 0.01 to 1.03 0.001 AUC, area under the curve=0.69.
BMI, body mass index; HDL, high-density lipoprotein.
- Table 7
Results of stepwise logistic regression for analysis of risk of impaired fasting glucose in normoglycemic participants for all triglyceride levels including Tg/HDL ratio
Variable/step number OR 95% CI p Value Gender (M) 1.69 1.37 to 2.00 <0.001 Age/10 1.57 1.44 to 1.70 <0.001 Family history 1.45 1.21 to 1.72 <0.001 BMI 1.08 1.06 to 1.10 <0.001 Tg/HDL ratio 1.05 1.03 to 1.11 0.001 AUC, area under the curve=0.67.
BMI, body mass index; HDL, high-density lipoprotein.
