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Southern Regional Meeting, New Orleans, February 18–20, 2016

DOI: 10.1136/jim-2015-000035.1 Published 28 January 2016
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    Abstract 21 Figure 1

    Photographs of the patient demonstrating abnormal anterior abdominal subcutaneous fat deposition alongside

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    Abstract 30 Figure 1

    MRI Brain (Image A) shows multiple flow voids in right frontal lobe on axial T2 image consistent with arterio-venous malformation. In addition, there are multiple hyperintense T2 signal areas (arrows) in the white matter bilaterally. Post-contrast axial MRI brain image (Image B) shows multiple tortuous enhancing vessels (arrow) in the right frontal lobe arteriovenous malformation

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    Abstract 50 Figure 1

    MRCP and CTscan showing a large congenital choledochal cyst ∼3.8 cm, and common bile duct dilation ∼4 cm, respectively.

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    Abstract 87 Figure 1

    TEE image of a large mass at the junction of the right atrium and SVC

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    Abstract 99 Figure 1

    Brain MRI

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    Abstract 112 Figure 1

    PET scan showing metastatic nodule in right clavicular region

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    Abstract 150 Figure 1

    Lymph node biopsy showing regressed germinal centers and interfollicular marked plasmacytosis and vascular proliferation

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    Abstract 272 Figure 1

    Patient's contrast MRI T2 and FLAIR images showing ADEM lesions of the periventricular white matter and bilateral frontal gyri.

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    Abstract 272 Figure 2

    Patient's helical chest CT image showing right pulmonary artery embolism with subsegmental involvement of the left side.

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    Abstract 275 Figure 1

    Growth Curves for Femoral Vein and Artery Diamter by Body Surface Area.

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    Abstract 283 Figure 1

    Frozen Magna Valve

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    Abstract 292 Figure 1

    Number of subjects and relative mortality in EL and PD group

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    Abstract 321 Figure 1

    Circulating IAI inversely correlated with SNAPPE-II scores

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    Abstract 330 Figure 1

    Comparing Mortality among Black and White Infants

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    Abstract 352 Figure 1

    A. Renal artery with intimal fibrosis. B. Glomerulus with fibrin thrombi. C. Duplication of GBM.

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    Abstract 353 Figure 1

    Transverse view of CT urogram with contrast demonstrating extensive bilateral angiomyolipomas with evidence of left hydronephrosis.

Tables

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  • Abstract 6 Table 1
    Primary AldosteronismNon-Primary Aldosteronism
    LVM (g/m2)IVS (mm)LVM (g/m2)IVS (mm)
    UNa<200
    (n=13)
    UNa≥200
    (n=7)
    UNa<200
    (n=13)
    UNa≥200
    (n=7)
    UNa<200
    (n=5)
    UNa≥200
    (n=9)
    UNa<200
    (n=5)
    UNa≥200
    (n=9)
    Baseline170.2175.812.411.0158.3205.111.613.4
    Difference between baseline, 3, and 6 month visits after addition of spironolactone
    Baseline to 3 months−34.8−16.0*−1.50.1−7.0−33.2*−0.4−0.7
    Baseline to 6 months−52.0−25.0*−1.40.5−19.8−40.5*1.2−1.4
    • * denotes statistical significance p<0.05

  • Abstract 9 Table 1
    PTHBNP25OHD
    HFpEF165.7±51.01369.1±383.421.2±2.5
    HFrEF89.7±13.01057.6±174.618.6±1.5
  • Abstract 54 Table 1

    Percent of Infants Observed or Identified with No risk on Three SIDS Prevention Level A recommendations

    Level A RecommendationsObserved
    Safe
    Family Map QuestionFamily Map Report SafeKappaCorrelation Coeffiicient, rN
    1. Back to sleep for every sleep74.3%Do you place your baby on his/her back to sleep at night or during naps?82.9%0.58**0.6035
    2. Room-sharing without bed-sharing is recommended81.0%Do you co-sleep with your baby at night? (Reverse)46.7%0360.4730
    3. Keep soft objects and loose bedding out of the crib42.1%Which of the following do you have in your home? Crib/Bed filled with soft bedding or lots of stuffed toys (Reverse)76.8%0.100.1738
    • **P<0.05

  • Abstract 60 Table 1
    All GroupsManualEZ-IO®Difference95% CIp-value
    Time to Placement (Min) Mean ESI 15.17 (N=12)11.14 (N=14)5.971.556–10.3970.010
    Standard Deviation46.21
  • Abstract 60 Table 2
    ≤ 8kgManualEZ-IO®Difference95% CIp-value
    Time to Placement (min) Mean ESI 14.5 (N=10)12.8 (N=5)8.31.892–14.7080.015
    Standard Deviation3.727
  • Abstract 61 Table 1
    CBC with DiffWBC: 4.53 x 10340% Segs, 26% Bands, 21 Lymphocyte, 11 Monocytes
    Creatinine, albumin, LFTsCr 3.5 (baseline), Alb 3.4, AST 19, ALT 12, Alk Phos 210
    C-RP, ESRC-RP 1.5, ESR 46
    Urine CultureNo growth
    Ulcer HSV stain/viral cultureNegative
    Serum HSV,EBV, CMV PCRNegative
    Bacterial/Fungal Blood and Wound CulturesNo growth
  • Abstract 100 Table 1
    1/20146/20149/2014
    LH18.816.79.2 mIU/ml (1.3–10.5)
    FSH23.08.88.7 mIU/ml (1.5–12.4)
    Estrogen185124183 pg/ml (40.0–115)
    Estradiol––53 pg/ml (7.6–42.8)
    Testosterone, Total142713281185 ng/dL (250–1100)
    Testosterone, Free1397.515.8 pg/mL (8.7–25.1)
    MRI-Unremarkable Sella, no enhancing pituitary mass
    Surgical Pathology-Gynecomastia, negative for atypia or malignancy
  • Abstract 108 Table 1

    Time course of laboratory data

    Day of admission12345678
    Absolute neutrophil count (cells/μL)6352120072210522
    Free T4 (ng/dL)1.81.822.53.34.53.73.3
    Thyroid stimulating hormone (mIU/L)<0.004<0.004<0.004<0.004<0.004<0.004<0.004<0.004
  • Abstract 224 Table 1

    Laboratory Values

    POD 1POD 2POD 3POD 4POD 5POD 6
    Daily serum sodium (mmol/L)135→129133–135134–137130–134137131
    Urine osmolality (mOsm/kg)673459
    Urine sodium (mmol/L)268217
    Urine output (mL/kg/hr)1.910.619.44.14.73.8
    Sodium intake (meq/kg/day)11.143.76022.72020
    Fluid balance (mL)836286351259038
    BNP (pg/mL)271.616.1
  • Abstract 234 Table 1

    Mean NTproBNP level (SEM) at 28, 32 and 36 weeks GA in the BPD and control group

    Gestational Age (weeks)Mean NTproBNP BPD group (pg/ml)Mean NTproBNP control group (pg/ml)p value
    284034±1131755±1620.04
    324434±1345751±1790.05
    364814±1368763±2290.05
  • Abstract 234 Table 2
    Gestational Age (weeks)Mean NTproBNP PAH by ECHO (pg/ml)Mean NTproBNP No PAH by ECHO (pg/ml)p value
    286210±22511603±4820.006
    327079±27681631±4950.006
    368190±29751953±6330.004
  • Abstract 282 Table 1

    One sample t-test for ECHO results

    % of patients with low abnormalMean valueLowest normal valuep-value
    SF23.836.48 %28 %
    EF28.667.71 %58 %
    LVEDD38.11.66 cm1.67 cm
  • Abstract 286 Table 1

    NEONATAL OUTCOMES

    OUTCOMEIUGR+FPI+ELBW
    n=23
    IUGR-FPI+ELBW
    n=35
    AGA+ELBW
    n=59
    Day 28 enteral, Kcal/Kg/day53.3±47.9*87.0±41.486.2±49.6 †
    36 week enteral, Kcal/Kg/day80.0±52.0106.8±49.0111.3±29.8 †
    TPN days46.2±34.2*46.2±34.2*29.3±28.5 †
    BPD, n(%)7(30)21(60)35(59)
    • *p<0.05 IUGR+FPI vs IUGR-FPI; †p<0.05 IUGR+FPI vs AGA+ELBW

  • Abstract 288 Table 1

    Measurement of biochemical activity of TF's in AF samples

    AF samplesSamples stored at 4°CSamples frozen to - 20C°
    EGF190±26.6165±22.96
    HGF8953±8057997±671
    TGF- α7.73±0.287.78±0.6
    Eotaxin4.23±0.614.49±0.77
    IL-688.72±24.46110±21.6
    IL-8129.6±26.68164.1±43.67
    IL1ra70±15.0194.91±18.74
    IP-101636±3771996±561.2
  • Abstract 289 Table 1

    Comparison of serum and transcutaneous bilirubin values

    Term (n=39)24 Hr.48 Hr.72 Hr.MeanDifference in mean from seum bili
    Serum Bili11.41111.311.20
    Tcb-C11.210.711.211+ 0.2
    Tcb-U5.85.44.95.4+ 5.8
    Preterm (n=71)
    Serum Bili98.27.78.30
    Tcb-C10.198.99.3−1.0
    Tcb-U9.36.96.37.5+ 0.8
    Extremely Preterm (n=15)
    Serum Bili3.83.32.83.30
    Tcb-C7.375.86.7−3.4
    TcB-U3.632.22.9+ 0.4
  • Abstract 292 Table 1

    PD related complications in both groups

    GroupBowel obstructionPerforationAdhesion/StricturesDrain complicationsOthers
    EL01001
    PD36223
  • Abstract 294 Table 1
    iNO group (n=57)Control group (n= 455)p value
    Birth weight
    (mean, SD)
    687, 240958, 295<0.001
    Gestation
    (mean, SD)
    25.5, 227.7, 2.7<0.001
    Afrian American race96.4%83.5%<0.01
    Male sex54.4%49%NS
    SGA status33.3%26.2%NS
    Antenatal Steroids96.5%92.1%NS
    5 minute APGAR<417.5%12.1%NS
    Medically/surgically treated PDA52.7%19.1%<0.001
    BPD (O2 at 36 weeks)61.5%17.6%<0.001
    Death22.8%7.25%<0.001
    BPD or Death74.3%26.5%<0.001
    • There was no difference in the incidence of ROP or NEC between the two groups

  • Abstract 297 Table 1

    Adjusted ORs for neonatal outcomes with initial postnatal hydrocortisone use over surgical ligation of PDA

    Death or BPD2.4 (0.6 - 9.7)0.23
    Need for ventilation at 36 weeks postconceptional age0.6 (0.1 – 4.0)0.60
  • Abstract 308 Table 1

    Percent Change in White Blood Cell count

    Suspected NECDefinite NEC
    N6937
    WBC (%)5 (−30 – 35)−41 (−68 – −13)*
    AMC (%)−8 (−47 – 82)−31 (−79 – 4)
    ANC (%)15 (−44 – 74)−64 (−90 – −26)*
    • % change from baseline are represented as median (25th–75th)

    • *p<0.05, definite NEC vs. suspected NEC

  • Abstract 320 Table 1
    Study PeriodFeeding TypeFrequency of Intolerance
    (n,%)
    MBMDHMFormulaDHMOther
    RTBW
    (n=37)
    39%55%6%1/37 (2.7%)1/37 (2.7%)
    Growth Period
    (n=37)
    36%29%35%0%3/37 (8.1%)
    Growth Period: DHM
    (n=27)
    19%71%10%0%0%
  • Abstract 320 Table 2
    Study PeriodWeight ChangeHead Change
    Under 2 kg
    (g/kg/day)
    2 kg - Discharge
    (g/day)

    (cm/week)
    Growth Period
    (n=37)
    17.1±3.030.0±7.40.9±0.2
    Growth Period: DHM
    (n=27)
    16.3±2.831.6±9.91.0±0.2
  • Abstract 325 Table 1
    N (Risk %)Crude HR (95% CI)Adjusted HR (95% CI)
    IVH Grade
    ≥ 135 (29.7)1.48 (0.70–3.14)1.42 (0.66–3.04)
    ≥ 218 (15.3)3.29 (1.25–8.64)2.98 (1.12–7.91)
    ≥ 313 (11.0)3.90 (1.23–12.34)3.50 (1.08–11.39)
    • * Estimated from a Cox proportional hazards regression and adjusted for birth weight, antenatal steroid use, and APGAR score

    • † AKI entered into model as a time-dependent covariate

  • Abstract 328 Table 1

    Baseline data

    VariableBody Cooling (n=25)Head Cooling (n=20)Body+Head Cooling (n=45)p-value
    Maternal Age (yrs)25.3 +–5.625.56 +– 5.724.9 +– 5.30.33
    Gestational Age (wks)38.2 +– 1.837.6 +– 1.837.9 +– 1.80.28
    Birthweight (kg)3.34+–1.032.97 +– 0.543.13 +– 806.80.13
    Apgar <5 at 5 min16 (80%)21 (84%)37 (82%)0.73
    Worst pH <60 min6.89 +– 0.186.91 +– 0.206.90 +– 0.190.73
    Worst BE <60 min−20.77 +– 6.87−18.17 +– 5.19−19.46 +– 6.150.20
    Cooling start (hrs)3.55 +– 1.473.74 +– 1.633.65 +– 1.540.69
    Seizures12 (60%)20 (80%)32 (71%)0.14
  • Abstract 344 Table 1
    Age – years (median)
    Sex – (% male)
    52
    81
    Race (%)
    Non-Hispanic Whites
    Non-Hispanic Blacks
    Other

    26
    72
    2
    Smoking History (%)
    Current smoker
    Former smoker
    Average pack years

    36
    45
    28
    Rheumatologic Conditions (n)
    Rheumatoid Arthritis
    Psoriasis
    Hidradenitis Supprativa
    Sarcoidosis
    Polymyositis
    Ankylosing Spondylitis
    Other

    14
    10
    7
    5
    2
    1
    3
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Southern Regional Meeting, New Orleans, February 18–20, 2016
Journal of Investigative Medicine Feb 2016, 64 (2) 488-634; DOI: 10.1136/jim-2015-000035.1

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Journal of Investigative Medicine Feb 2016, 64 (2) 488-634; DOI: 10.1136/jim-2015-000035.1
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