Model 1-Mechanical ventilation alone vs unused |
Age (years) | 0.98 (0.95 to 1.02) | 0.374 | | |
Gender (ref=female) | 1.43 (0.44 to 4.63) | 0.552 | | |
Type of TBI (ref=epidural hematoma) |
Subdural hematoma | 2.48 (0.6 to 10.27) | 0.212 | | |
Intracerebral hematoma plus cerebral contusion | 1.8 (0.37 to 8.68) | 0.464 | | |
Diffuse axonal injury | 0.9 (0.12 to 6.78) | 0.919 | | |
Hypoxemia on admission (ref=no) | 1.14 (0.15 to 8.76) | 0.902 | 0.66 (0.07 to 6.11) | 0.717 |
Operation(ref=no) | 2.2 (0.61 to 7.99) | 0.231 | | |
APACHE (on admission) | 1.3 (1.08 to 1.56) | 0.005* | 1.33 (1.1 to 1.61) | 0.003* |
Albumin (on admission) | 0.92 (0.77 to 1.1) | 0.358 | | |
GCS (on admission) | 1.15 (0.74 to 1.76) | 0.537 | | |
Mean arterial pressure during the hospital stay (mm Hg) | 1.01 (0.97 to 1.06) | 0.525 | 1.03 (0.98 to 1.09) | 0.264 |
Adrenal insufficiency (ref=no) | 1.6 (0.32 to 8.01) | 0.567 | 1.59 (0.23 to 10.77) | 0.636 |
Incidence of shock (ref=no) | 1.14 (0.15 to 8.76) | 0.902 | 1.16 (0.09 to 15.43) | 0.912 |
Model 2-Mechanical ventilation plus sedation vs unused |
Age (years) | 0.998 (0.97 to 1.03) | 0.890 | | |
Gender (ref=female) | 1.08 (0.38 to 3.09) | 0.888 | | |
Type of TBI (ref= epidural hematoma) |
Subdural hematoma | 1.41 (0.37 to 5.32) | 0.616 | | |
Intracerebral hematoma plus cerebral contusion | 1.88 (0.47 to 7.53) | 0.375 | | |
Diffuse axonal injury | 1.69 (0.35 to 8.22) | 0.517 | | |
Hypoxemia on admission (ref=no) | 5.21 (1.03 to 26.27) | 0.046* | 2.99 (0.48 to 18.76) | 0.243 |
Operation(ref=no) | 3.08 (0.94 to 10.1) | 0.063 | | |
APACHE (on admission) | 1.14 (0.97 to 1.35) | 0.110 | 1.1 (0.92 to 1.3) | 0.297 |
Albumin (on admission) | 0.93 (0.79 to 1.1) | 0.416 | | |
GCS (on admission) | 1.004 (0.66 to 1.52) | 0.983 | | |
Mean arterial pressure during the hospital stay (mm Hg) | 0.97 (0.93 to 1.01) | 0.159 | 1.002 (0.95 to 1.05) | 0.944 |
Adrenal insufficiency (ref=no) | 4.95 (1.24 to 19.79) | 0.024* | 1.62 (0.29 to 9.03) | 0.583 |
Incidence of shock (ref=no) | 7.74 (1.57 to 38.24) | 0.012* | 5.05 (0.65 to 39.1) | 0.121 |
Model 3-Mechanical ventilation plus sedation vs mechanical ventilation alone |
Age (years) | 1.01 (0.98 to 1.05) | 0.421 | | |
Gender (ref=female) | 0.75 (0.24 to 2.33) | 0.625 | | |
Type of TBI (ref= epidural hematoma) | | | | |
Subdural hematoma | 0.57 (0.14 to 2.32) | 0.431 | | |
Intracerebral hematoma plus cerebral contusion | 1.04 (0.23 to 4.7) | 0.958 | | |
Diffuse axonal injury | 1.87 (0.27 to 13.2) | 0.528 | | |
Hypoxemia on admission (ref=no) | 4.58 (0.9 to 23.27) | 0.066 | 4.51 (0.73 to 27.8) | 0.105 |
Operation(ref=no) | 1.4 (0.47 to 4.16) | 0.545 | | |
APACHE (on admission) | 0.88 (0.75 to 1.03) | 0.116 | 0.82 (0.69 to 0.99) | 0.034* |
Albumin (on admission) | 1.02 (0.85 to 1.21) | 0.850 | | |
GCS (on admission) | 0.88 (0.58 to 1.32) | 0.527 | | |
Mean arterial pressure during the hospital stay (mm Hg) | 0.96 (0.92 to 0.9994) | 0.047* | 0.97 (0.92 to 1.03) | 0.297 |
Adrenal insufficiency (ref=no) | 3.1 (0.86 to 11.1) | 0.083 | 1.02 (0.19 to 5.59) | 0.983 |
Incidence of shock (ref=no) | 6.81 (1.37 to 33.87) | 0.019* | 4.36 (0.48 to 39.91) | 0.192 |