Systemic amyloidosis is a syndrome of protean manifestations and many pathophysiologies, united by the histopathologic demonstration of extracellular deposition of Congo red-positive fibrillar material that shows apple green birefringence under polarized light microscopy.1 Its clinical features vary depending on the site of amyloid deposition and the particular protein of which amyloid is comprised. Symptomatic deposition of amyloid may involve the heart, the liver, the kidneys, the stomach and intestines; the central, peripheral, or autonomic nervous systems; the lungs or upper airway; or the skin.1 Familial Mediterranean fever is an autosomal recessive disorder of amyloid deposition.2
Since it can present in so many …
Log in using your username and password
Log in through your institution
PURCHASE SHORT TERM ACCESS
Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$37.00
Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.
