Article Figures & Data
- Table 1
Ultrasound scores of patients with rheumatoid arthritis at different time points
Ultrasonographic appearances Baseline 3 months 6 months 12 months Synovial hypertrophy 12.66±9.579 9.33±8.107 8.84±7.267 8.34±7.618 Power Doppler signal 4.00 (1.00–8.00) 2.00 (0.00–5.00) 2.00 (0.00–5.00) 2.00 (0.00–6.00) Bone erosions 1.00 (0.00–5.00) 1.00 (0.00–5.00) 2.00 (0.00–5.50) 2.00 (0.00–6.00) - Table 2
Interobserver agreement
Ultrasonographic factors Kappa ICC Overall agreement Synovial hypertrophy 0.78 0.91 88.9 Power Doppler signal 0.75 0.82 87.4 Bone erosions 0.67 0.86 79.8 ICC, intraclass correlation coefficient.
- Table 3
Univariate and multivariate analyses of baseline ultrasonographic factors for predicting ultrasound-detected structural damage
Ultrasonographic factors at baseline Univariate Multivariate OR (95% CI) P value OR (95% CI) P value Synovial hypertrophy 0.931 (0.875 to 0.991) 0.024 0.910 (0.822 to 1.008) 0.071 Power Doppler signal 0.937 (0.862 to 1.019) 0.128 1.040 (0.910 to 1.188) 0.566 Bone erosions 0.960 (0.852 to 1.081) 0.502 - Table 4
Performance of clinical and ultrasound remission in identifying patients with non-progressive ultrasonography-detected structural damage
Prevalence of non-progressive ultrasonography-detected structural damage P value OR (95% CI) Sensitivity Specificity PPV NPV Patients in remission
n/N (%)Patients not in remission
n/N (%)Ultrasound remission at 3 months 17/19 (89.47) 20/42 (47.62) 0.006 9.350 (1.916 to 45.638) 45.95 91.67 89.47 52.38 Ultrasound remission at 6 months 19/22 (86.36) 18/39 (46.15) 0.004 7.389 (1.876 to 29.100) 51.35 87.50 86.36 53.85 Clinical remission at 3 months 18/23 (78.26) 19/38 (50.00) 0.029 3.600 (1.109 to 11.684) 48.65 79.17 78.26 50.00 Clinical remission at 6 months 15/20 (75.00) 23/41 (56.10) 0.153 2.348 (0.718 to 7.681) 39.47 78.26 75.00 43.90 NPV, negative predictive value; PPV, positive predictive value.
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