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Open Access

Analysis of the characteristics of blood lipid metabolism in twin pregnancy

Yanqin Lou, Pei He, Huijun Jiang, Li Xiang, Xuemei Gao
DOI: 10.1136/jim-2022-002412 Published 22 September 2022
Yanqin Lou
Department of Obstetrics, Wuhan No 1 Hospital, Wuhan, Hubei, China
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Pei He
Department of Obstetrics, Wuhan No 1 Hospital, Wuhan, Hubei, China
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Huijun Jiang
Department of Obstetrics, Wuhan No 1 Hospital, Wuhan, Hubei, China
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Li Xiang
Department of Obstetrics, Wuhan No 1 Hospital, Wuhan, Hubei, China
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Xuemei Gao
Department of Obstetrics, Wuhan No 1 Hospital, Wuhan, Hubei, China
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Article Figures & Data

Tables

  • Table 1

    Comparison of general data between twin pregnancy and singleton pregnancy

    GroupsCasesAge (y Embedded Image±s)Gravidity (Embedded Image±s)Parity (Embedded Image±s)BMI (kg/m2)Conception methodGDM (n)PIH (n)
    NaturallyAssisted reproductive technologyYesNoYesNo
    Singleton pregnancy23228.62±3.413.15±0.620.82±0.5621.54±2.76151813020222210
    Twin pregnancy9630.83±4.103.21±0.640.81±0.6323.12±3.05623422741878
     t/χ24.9271.8471.0504.7500.0085.0755.446
     P value0.0000.0660.2950.0000.9310.0310.026
    • BMI, body mass index; GDM, gestational diabetes mellitus; PIH, pregnancy-induced hypertension.

  • Table 2

    Changes of the TG level and the TC level in the first, second and third trimesters of twin pregnancy (mmol/L, Embedded Image±s)

    TGTC
    The first trimester1.46±0.304.29±0.07
    The second trimester3.19±1.116.31±1.32
    The third trimester3.58±1.106.47±1.30
    F146.287109.410
    p10.0000.000
    p20.0040.347
    p30.0000.000
    • Note: p1 meant comparison between the first trimester and the second trimester; p2 meant comparison between the second trimester and the third trimester; p3 meant comparison between the first trimester and the third trimester.

    • TC, total cholesterol; TG, triglyceride.

  • Table 3

    Comparison of the TG level and the TC level between twin pregnancy and singleton pregnancy (mmol/L, Embedded Image±s)

    TGTC
    Elderly groupAge groupElderly groupAge group
    The first trimesterSingleton1.21±0.51 (n=34)1.13±0.42 (n=198)4.20±0.68 (n=34)4.18±0.73 (n=198)
    Twin1.49±0.48 (n=41)1.42±0.57 (n=55)4.31±0.65 (n=41)4.28±0.71 (n=55)
    t6.2736.3521.4531.298
    P value0.0000.0000.2680.347
    The second trimesterSingleton2.32±0.86 (n=34)2.25±0.73 (n=198)6.27±1.77 (n=34)6.14±2.21 (n=198)
    Twin3.47±1.09 (n=41)3.06±1.24 (n=55)6.32±1.96 (n=41)6.25±1.13 (n=55)
    t7.4267.6831.3721.012
    P value0.0000.0000.3860.272
    The third trimesterSingleton3.08±0.98 (n=34)2.94±1.06 (n=198)6.38±1.43 (n=34)6.33±1.71 (n=198)
    Twin3.59±1.12 (n=41)3.52±1.04 (n=55)6.47±1.02 (n=41)6.43±1.39 (n=55)
    t3.2874.6520.5720.546
    P value0.0000.0000.4820.516
    • TC, total cholesterol; TG, triglyceride.

  • Table 4

    Comparison of the TG level and the TC level between the GDM group and the non-GDM group in twin pregnancy

    GroupsCasesThe first trimesterThe second trimesterThe third trimester
    TGTCTGTCTGTC
    The GDM group221.58±0.394.37±0.673.85±1.136.18±1.094.13±1.246.59±1.28
    The non-GDM group741.42±0.284.27±0.672.99±1.036.35±1.383.41±1.006.43±1.31
     t2.3230.6213.3240.5302.7950.525
     P value0.0200.5230.0010.5970.0060.601
    • GDM, gestational diabetes mellitus; TC, total cholesterol; TG, triglyceride.

  • Table 5

    Comparison of the TG level and the TC level between the PIH group and the non-PIH group in twin pregnancy (mmol/L, Embedded Image±s)

    GroupsCasesThe first trimesterThe second trimesterThe third trimester
    TGTCTGTCTGTC
    The PIH group181.62±0.354.34±0.853.92±1.096.24±1.124.18±1.196.61±1.35
    The non-PIH group781.45±0.344.33±0.792.95±1.056.32±1.273.39±1.096.41±1.26
     t2.4650.6373.4530.5422.3780.486
     P value0.0020.4960.0050.5680.0040.592
    • PIH, pregnancy-induced hypertension; TC, total cholesterol; TG, triglyceride.

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Analysis of the characteristics of blood lipid metabolism in twin pregnancy
Yanqin Lou, Pei He, Huijun Jiang, Li Xiang, Xuemei Gao
Journal of Investigative Medicine Sep 2022, jim-2022-002412; DOI: 10.1136/jim-2022-002412

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Analysis of the characteristics of blood lipid metabolism in twin pregnancy
Yanqin Lou, Pei He, Huijun Jiang, Li Xiang, Xuemei Gao
Journal of Investigative Medicine Sep 2022, jim-2022-002412; DOI: 10.1136/jim-2022-002412
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Analysis of the characteristics of blood lipid metabolism in twin pregnancy
Yanqin Lou, Pei He, Huijun Jiang, Li Xiang, Xuemei Gao
Journal of Investigative Medicine Sep 2022, jim-2022-002412; DOI: 10.1136/jim-2022-002412
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