Open Access
Bioinformatic and experimental methods to identify and validate bacterial RNA-human RNA interactions
Kylie I Krohmaly, Robert J Freishtat, Andrea L Hahn
DOI: 10.1136/jim-2022-002509 Published 26 September 2022
Kylie I Krohmaly
1Center for Genetic Medicine Research, Children's National Research Institute, Washington, District of Columbia, USA
2Institute for Biomedical Sciences, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA
Robert J Freishtat
1Center for Genetic Medicine Research, Children's National Research Institute, Washington, District of Columbia, USA
3Division of Emergency Medicine, Children's National Hospital, Washington, District of Columbia, USA
4Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA
Andrea L Hahn
1Center for Genetic Medicine Research, Children's National Research Institute, Washington, District of Columbia, USA
4Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA
5Division of Infectious Diseases, Children's National Hospital, Washington, District of Columbia, USA
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Bioinformatic and experimental methods to identify and validate bacterial RNA-human RNA interactions
Kylie I Krohmaly, Robert J Freishtat, Andrea L Hahn
Journal of Investigative Medicine Sep 2022, jim-2022-002509; DOI: 10.1136/jim-2022-002509
- Article
- Abstract
- Section 1: background and evidence of bacteria-to-human communication via small RNAs
- Section 2: bioinformatic approaches for predicting bacterial sRNA-human mRNA interactions
- Section 3: experimental approaches for identifying and validating bacterial sRNA-human mRNA interactions
- Conclusion
- Ethics statements
- Footnotes
- References
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