@article {Iqbal391, author = {Usman Iqbal and Hsuan-Chia Yang and Wen-Shan Jian and Yun Yen and Yu-Chuan (Jack) Li}, title = {Does aspirin use reduce the risk for cancer?}, volume = {65}, number = {2}, pages = {391--392}, year = {2017}, doi = {10.1136/jim-2016-000275}, publisher = {BMJ Publishing Group Limited}, abstract = {Recently, studies have reported that aspirin has chemopreventive properties. In this study, we used the Taiwan NHI database, which covers a population of 23 million (99.99\%) Taiwanese from 2001 to 2011. This was a case{\textendash}control study which identified 601,733 patients using ICD-9-CM codes who were diagnosed with cancer. Each case with 4 eligible controls was matched for age, sex, and index date and adjusted for confounding factors. The observed overall cancer risk (adjusted OR (AOR), 0.95; 95\% CI 0.94 to 0.96) reduced with aspirin use, specifically, colorectal (AOR, 0.97; 95\% CI 0.94 to 0.99) and digestive system (AOR, 0.96; 95\% CI 0.94 to 0.98) cancers. Findings from the Asian population would contribute to the discussion on aspirin{\textquoteright}s safety profile.}, issn = {1081-5589}, URL = {http://hw-f5-jim.highwire.org/content/65/2/391}, eprint = {http://hw-f5-jim.highwire.org/content/65/2/391.full.pdf}, journal = {Journal of Investigative Medicine} }