%0 Journal Article %A Cuiwen He %A Loren G Fong %A Stephen G Young %A Haibo Jiang %T NanoSIMS imaging: an approach for visualizing and quantifying lipids in cells and tissues %D 2017 %R 10.1136/jim-2016-000239 %J Journal of Investigative Medicine %P 669-672 %V 65 %N 3 %X Over the past few decades, several approaches have been used to image lipids in cells and tissues, but most have limited spatial resolution and sensitivity. Here, we discuss a relatively new approach, nanoscale secondary ion mass spectrometry imaging, that makes it possible to visualize lipids in cells and tissues in a quantitative fashion and with high spatial resolution and high sensitivity. %U http://hw-f5-jim.highwire.org/content/jim/65/3/669.full.pdf