RT Journal Article SR Electronic T1 4 Research on the change of heart rate variability under strong noise stimulation JF Journal of Investigative Medicine JO J Investig Med FD BMJ Publishing Group Ltd SP A2 OP A2 DO 10.1136/jim-2019-000994.4 VO 67 IS Suppl 1 A1 L Lu A1 HW Zhuang A1 YL Zhang YR 2019 UL http://hw-f5-jim.highwire.org/content/67/Suppl_1/A2.2.abstract AB Objective To investigate the effect of different strong noise stimuli on heart rate variability (HRV) in 5 min.Methods 120 students aged 19–22 years with no diseases were selected; they had not done strenuous exercise within 24 hours. The subjects were divided into four groups of 30 people. Each group was stimulated by white noise for 5 min as follows: group A 105 dB, group B 100 dB, group C 115 dB, group D was the control group. A 1 hour ambulatory ECG was conducted in the four groups. The 5 min average HR, SDNN, PNN50, HF, LF and VLF were measured or calculated.Results The levels of SDNN, PNN50, LF and VLF of groups A, B and C were significantly lower than those in the control group, while HR was significantly higher than that in the control group (p<0.05). For PNN50, LF and VLF, group C had the lowest values and group A had the highest values.Conclusion HRV of people exposed to noise appears blunted significantly, which suggests that long-term and regular exposure to strong noise not only harms the auditory system, but also may result in impairment of cardiac autonomic nerve activity.