PT  - JOURNAL ARTICLE
AU  - James H Clark
AU  - Sharon Pang
AU  - Robert M Naclerio
AU  - Matthew Kashima
TI  - Complications of nasal SARS-CoV-2 testing: a review
AID  - 10.1136/jim-2021-001962
DP  - 2021 Aug 04
TA  - Journal of Investigative Medicine
PG  - jim-2021-001962
4099  - http://hw-f5-jim.highwire.org/content/early/2021/08/03/jim-2021-001962.short
4100  - http://hw-f5-jim.highwire.org/content/early/2021/08/03/jim-2021-001962.full
AB  - Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs.