TY - JOUR T1 - Complications of nasal SARS-CoV-2 testing: a review JF - Journal of Investigative Medicine JO - J Investig Med DO - 10.1136/jim-2021-001962 SP - jim-2021-001962 AU - James H Clark AU - Sharon Pang AU - Robert M Naclerio AU - Matthew Kashima Y1 - 2021/08/04 UR - http://hw-f5-jim.highwire.org/content/early/2021/08/03/jim-2021-001962.abstract N2 - Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs. ER -