RT Journal Article SR Electronic T1 Depressive symptomatology in adults during the COVID-19 pandemic JF Journal of Investigative Medicine JO J Investig Med FD BMJ Publishing Group Ltd SP 436 OP 445 DO 10.1136/jim-2021-001992 VO 70 IS 2 A1 Álvaro Alexander Ocampo González A1 Javier Ferney Castillo García A1 Laura Carolina Pabón Sandoval A1 José Rafael Tovar Cuevas A1 Sirsa Aleyda Hidalgo Ibarra A1 Diego Alejandro Calle Sandoval A1 Edwin Cortés González A1 Kevin Steven Garcia Chica A1 Jonnathan Steven Pabón Lozano A1 María del Carmen Muñoz Rico YR 2022 UL http://hw-f5-jim.highwire.org/content/70/2/436.abstract AB Depression entails changes in the mental health of individuals worldwide. Episodes of depression lead to mood swings and changes in the motivational dimension. Our research focused on the prevalence of depression in the adult population and on how it affected the social and affective dimensions. Owing to the current pandemic, we deemed it necessary to explore how protective measures against COVID-19 infection, such as quarantines, could be related to mental health. Moreover, we found it important to determine the prevalence of depressive and anxious symptomatology in adults from the Valle del Cauca region in Colombia during the social isolation connected to COVID-19. Our study was descriptive, analytical and cross-sectional, and involved 1248 subjects. As tools, we used the Hamilton Depression Rating Scale and the Hamilton Anxiety Rating Scale. The data demonstrated that women were more likely to display symptoms of depression and that individuals aged between 24 and 29 were less likely to reveal symptoms of anxiety than those aged between 18 and 23. Moreover, childless or economically dependent individuals proved to be more likely to display symptoms of depression during the pandemic.All data relevant to the study are included in the article or uploaded as supplementary information. Data are not available as they are confidential.