TY - JOUR T1 - Correspondence on ‘Low-dose thrombolysis for submassive pulmonary embolism’ by Yilmaz and Uzun JF - Journal of Investigative Medicine JO - J Investig Med DO - 10.1136/jim-2022-002420 SP - jim-2022-002420 AU - Ahmet Güner AU - Fatih Uzun AU - Ezgi Gültekin Güner AU - Cemalettin Akman AU - Mehmet Ertürk Y1 - 2022/08/10 UR - http://hw-f5-jim.highwire.org/content/early/2022/08/09/jim-2022-002420.abstract N2 - To the Editor,We recently read with great interest the article by Yilmaz and Uzun,1 describing the efficacy and safety of low dose thrombolytic therapy (TT) in patients with acute submassive pulmonary embolism (PE). We would like to emphasize a few points in light of current evidence.PE is one of the most frequently reported thrombotic complications,2 and is more prevalent in critically ill patients with coronavirus disease 2019 (COVID-19). Thirty-day results have shown that patients with COVID-19 and PE received no significant benefit from empirically administered prophylactic anticoagulants at moderate doses against venous thrombosis or mortality.3 In submassive … ER -