RT Journal Article
SR Electronic
T1 Clinical characteristics and social determinants of health associated with 30-day hospital readmissions of patients with COVID-19
JF Journal of Investigative Medicine
JO J Investig Med
FD BMJ Publishing Group Ltd
SP 1406
OP 1415
DO 10.1136/jim-2022-002344
VO 70
IS 6
A1 Zanthia Wiley
A1 Ambar Kulshreshtha
A1 Dong Li
A1 Julianne Kubes
A1 Sheetal Kandiah
A1 Serena Leung
A1 Ketino Kobaidze
A1 Sangmin Ryan Shin
A1 Abeer Moanna
A1 Jonathan Perkins
A1 Matthew Hogan
A1 Kanika M Sims
A1 Tolu Amzat
A1 Valeria D Cantos
A1 Temitope Elutilo-Ayoola
A1 Jasmah Hanna
A1 Nadine M Harris
A1 Tracey L Henry
A1 Onyinye Iheaku
A1 Mariam Japaridze
A1 Vaishnavi Lanka
A1 Theresa A Johnson
A1 Nkechi Mbaezue
A1 Paulina A Rebolledo
A1 Mary Elizabeth Sexton
A1 Phani Keerthi Surapaneni
A1 Nicole Franks
YR 2022
UL http://hw-f5-jim.highwire.org/content/70/6/1406.abstract
AB COVID-19 readmissions are associated with increased patient mortality and healthcare system strain. This retrospective cohort study of PCR-confirmed COVID-19 positive adults (>18 years) hospitalized and readmitted within 30 days of discharge from index admission was performed at eight Atlanta hospitals from March to December 2020. The objective was to describe COVID-19 patient-level demographics and clinical characteristics, and community-level social determinants of health (SDoH) that contribute to 30-day readmissions. Demographics, comorbidities, COVID-19 treatment, and discharge disposition data were extracted from the index admission. ZIP codes were linked to a demographic/lifestyle database interpolating to community-level SDoH. Of 7155 patients with COVID-19, 463 (6.5%) had 30-day, unplanned, all-cause hospital readmissions. Statistically significant differences were not found in readmissions stratified by age, sex, race, or ethnicity. Patients with a high-risk Charlson Comorbidity Index had higher odds of readmission (OR 4.8 (95% CI: 2.1 to 11.0)). Remdesivir treatment and intensive care unit (ICU) care were associated with lower odds of readmission (OR 0.5 (95% CI: 0.4 to 0.8) and OR 0.5 (95% CI: 0.4 to 0.7), respectively). Patients residing in communities with larger average household size were less likely to be readmitted (OR 0.7 (95% CI: 0.5 to 0.9). In this cohort, patients who received remdesivir, were cared for in an ICU, and resided in ZIP codes with higher proportions of residents with increased social support had lower odds of readmission. These patient-level factors and community-level SDoH may be used to identify patients with COVID-19 who are at increased risk of readmission.All data relevant to the study are included in the article or uploaded as supplementary information.