RT Journal Article
SR Electronic
T1 Vitamin D Levels in Patients With Type 2 Diabetes Mellitus
JF Journal of Investigative Medicine
JO J Investig Med
FD BMJ Publishing Group Ltd
SP 921
OP 923
DO 10.1097/JIM.0000000000000234
VO 63
IS 8
A1 José María Calvo-Romero
A1 José Manuel Ramiro-Lozano
YR 2015
UL http://hw-f5-jim.highwire.org/content/63/8/921.abstract
AB Background Vitamin D may influence many diseases, including type 2 diabetes mellitus.Patients and Methods We studied serum levels of 25-hydroxyvitamin D (25(OH)D) and associated characteristics in type 2 diabetic outpatients with pharmacologic treatment attended in internal medicine offices in a first-level hospital from Extremadura (Southern Spain).Results We included a total of 103 patients. Seventy-two patients (69.9%) had serum levels of 25(OH)D lower than 20 ng/mL. There was inverse correlation between serum levels of 25(OH)D and glycosylated hemoglobin (r = −0.74, P = 0.01). In 78 patients without insulin therapy, we found inverse correlation between serum levels of 25(OH)D and fasting serum insulin (r = −0.82, P = 0.001) and Homeostasis Model Assessment–Insulin Resistance (r = −0.51, P < 0.001).Conclusions Vitamin D deficiency is common in type 2 diabetic patients. There are inverse correlations between vitamin D and metabolic control and insulin resistance.