All patients | C. difficile | |||||
---|---|---|---|---|---|---|
Absent | Present | |||||
Outcomes | Count | Per cent | N | Per cent | N | Per cent |
Died | 176,681 | 42.01 | 164,402 | 40.89 | 12,279 | 68.78 |
Colectomy | 403 | 0.1 | 296 | 0.07 | 107 | 0.6 |
HR of death | ||||||
95% CI | ||||||
HR | Lower | Upper | ||||
Increased risk for mortality* | ||||||
C. difficile colitis | 1.8 | 1.77 | 1.83 | |||
≥65 years | 2.28 | 2.25 | 2.3 | |||
Cirrhosis | 1.76 | 1.71 | 1.81 | |||
HIV | 1.39 | 1.32 | 1.46 | |||
GI bleeding | 1.31 | 1.29 | 1.33 | |||
Laparotomy | 1.25 | 1.18 | 1.33 | |||
Urosepsis | 1.18 | 1.16 | 1.19 | |||
UTI | 1.14 | 1.12 | 1.16 | |||
HCV | 1.13 | 1.1 | 1.17 | |||
Leucopenia | 1.124 | 1.055 | 1.198 | |||
Duodenal ulcer | 1.085 | 1.045 | 1.127 | |||
Year of first ESRD service | ||||||
2005 | 1.00 | NA | NA | |||
2006 | 1.07 | 1.03 | 1.12 | |||
2007 | 1.36 | 1.29 | 1.43 | |||
2008 | 1.74 | 1.63 | 1.85 | |||
Decreased risk for mortality* | ||||||
Osteomyelitis | 0.946 | 0.921 | 0.972 | |||
Esophagitis | 0.906 | 0.874 | 0.939 | |||
Esophageal reflux | 0.811 | 0.799 | 0.824 | |||
Diverticulitis | 0.746 | 0.724 | 0.767 | |||
Black | 0.723 | 0.715 | 0.731 | |||
PD | 0.656 | 0.641 | 0.672 | |||
Hispanic | 0.652 | 0.641 | 0.662 | |||
Kidney transplant | 0.133 | 0.124 | 0.142 |
*Each covariate was present at or after the start of dialysis.
aHR, adjusted HR; ESRD, end-stage renal disease; GI, gastrointestinal; HCV, hepatitis C virus; PD, peritoneal dialysis; UTI, urinary tract infection.