Table 3

Association of Klotho and FGF-23 levels with serum parameters of mineral metabolism in ADPKD

Soluble α-Klotho
r (p) values
FGF-23
r (p) values
Age0.17 (0.14)0.17 (0.44)
Calcium0.009 (0.94)0.009 (0.94)
Phosphate0.19 (0.12)0.19 (0.12)
25(OH)D30.27 (0.025)0.19 (0.11)
iPTH0.025 (0.85)0.025 (0.85)
ALP0.27 (0.88)0.27 (0.88)
FGF-230.818 (0.001)
UPCR−0.019 (0.87)−0.019 (0.87)
eGFR−0.251 (0.034)−0.251 (0.034)
  • 25(OH)D3, 25-hydroxyvitamin D3; ADPKD, autosomal dominant polycystic kidney disease; ALP, alkaline phosphatase; eGFR, estimated glomerular filtration rate; FGF-23, fibroblast growth factor-23; iPTH, intact parathyroid hormone; UPCR, urinary protein to creatinine ratio.