Univariable and multivariable hazards of incident diabetes
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| SVR (Ref—no) | ||||||
| Yes | 0.56 | 0.45 to 0.68 | <0.001 | 0.60 | 0.48 to 0.74 | <0.001 |
| Age (years) (Ref—≤50) | ||||||
| >50 | 1.35 | 1.13 to 1.62 | 0.001 | 1.24 | 1.03 to 1.49 | 0.02 |
| Gender (Ref—female) | ||||||
| Male | 1.19 | 0.75 to 1.88 | 0.46 | 0.89 | 0.55 to 1.42 | 0.61 |
| Race (Ref—Caucasian) | ||||||
| African-American | 1.23 | 1.00 to 1.51 | 0.06 | 1.19 | 0.95 to 1.48 | 0.13 |
| Others | 1.04 | 0.80 to 1.35 | 0.78 | 1.09 | 0.84 to 1.42 | 0.53 |
| Ethnicity (ref—NH/L) | ||||||
| Hispanic/Latino | 1.00 | 0.78 to 1.31 | 0.96 | 1.01 | 0.77 to 1.32 | 0.96 |
| Body mass index (Ref—<30) | ||||||
| ≥30 kg/m2 | 1.90 | 1.60 to 2.24 | <0.001 | 1.71 | 1.44 to 2.03 | <0.001 |
| ALT (Ref—≤40) | ||||||
| >40 IU/L | 1.15 | 0.93 to 1.42 | 0.21 | 1.03 | 0.83 to 1.28 | 0.82 |
| Glucose (Ref—<100) | ||||||
| ≥100 mg/dL | 2.38 | 2.00 to 2.84 | <0.001 | 2.13 | 1.78 to 2.54 | <0.001 |
| HDL (Ref—<40) | ||||||
| ≥40 mg/dL | 0.74 | 0.63 to 0.88 | <0.001 | 0.87 | 0.72 to 1.04 | 0.12 |
| Triglyceride (Ref—<150) | ||||||
| ≥150 mg/dL | 1.47 | 1.24 to 1.75 | <0.001 | 1.33 | 1.12 to 1.60 | <0.01 |
| Hypertension (Ref—no) | ||||||
| Yes | 1.47 | 1.22 to 1.76 | <0.001 | 1.28 | 1.07 to 1.54 | <0.01 |
| FIB4-score (Ref—≤3.25) | ||||||
| >3.25 | 1.65 | 1.35 to 2.01 | <0.01 | 1.49 | 1.21 to 1.83 | <0.001 |
| Genotype (Ref—1) | ||||||
| 2 | 0.81 | 0.63 to 1.05 | 0.11 | 1.06 | 0.81 to 1.39 | 0.68 |
| 3 | 0.73 | 0.51 to 1.05 | 0.09 | 0.94 | 0.65 to 1.37 | 0.75 |
ALT, alanine transaminase; HDL, high-density lipoprotein; NH/L, non-Hispanic/Latino; SVR, sustained virological response.