Demographic, clinical, and echocardiographic characteristics of the patients with hypertrophic cardiomyopathy included in the study
| Men/women (% men) | 134/78 (63) |
|---|---|
| Age (years) | 52±17 |
| Age at onset (years) | 47±17 |
| BMI (kg/m2) | 27±5 |
| Family history, n (%) | |
| Hypertrophic cardiomyopathy | 63 (30) |
| Sudden cardiac death | 35 (16.5) |
| Clinical symptoms, n (%) | |
| Angina | 64 (30) |
| Syncope | 35 (16.5) |
| Dyspnea | 124 (58) |
| NYHA index | |
| Class I–II | 93 (75) |
| Class III–IV | 31 (25) |
| Echocardiographic data | |
| Interventricular septum (mm) | 20±5 |
| Posterior wall (mm) | 14±3 |
| LVOTO, n (%) | 95 (45) |
| Sarcomeric mutation, n (%) | 70 (33) |
| MYBPC3 | 37 (52.9) |
| MYH7 | 23 (32.9) |
| TNNT2 | 4 (5.7) |
| TNNI3 | 2 (2.9) |
| TPM1 | 1 (1.4) |
| ACTC1 | 1 (1.4) |
| MYL2 | 1 (1.4) |
| MYBPC3 + TNNT2 | 1 (1.4) |
Categorical variables are shown as number of patients (%). Quantitative variables are shown as mean±SD.
BMI, body mass index; LVOTO, left ventricular outflow tract obstruction; NYHA, New York Heart Association functional class.