Risk factors associated with death and ESRD (Cox regression analysis)
| ESRD | Death | |||
| csHR (95% CI) | p Value | csHR (95% CI) | p Value | |
| Baseline | ||||
| Age, years | 0.95 (0.91 to 1.00) | 0.049 | 1.04 (1.01 to 1.07) | 0.004 |
| Creatinine (>1.6 vs <1.6 mg/dL) | 3.64 (1.58 to 8.38) | 0.002 | 2.27 (1.44 to 3.57) | <0.001 |
| Hb (<11.0 vs >11.0 g/dL) | 2.72 (1.35 to 5.49) | 0.005 | 2.20 (1.49 to 3.26) | <0.001 |
| CCI score | ||||
| (3–4 vs 1–2) (≥5 vs 1–2) | 0.55 (0.22 to 1.39) 0.80 (0.33 to 1.96) | 0.205 0.626 | 1.35 (0.80 to 2.29) 2.82 (1.70 to 4.67) | 0.258 <0.001 |
| Peripheral vascular disease (yes vs no) | 3.60 (1.70 to 7.60) | 0.001 | 1.03 (0.64 to 1.68) | 0.890 |
| DM vs other CKD etiologies | 1.75 (0.85 to 3.58) | 0.127 | 1.02 (0.67 to 1.55) | 0.930 |
| During the follow-up | ||||
| Hospitalizations (yes vs no) | 1.72 (1.17 to 2.52) | 0.006 | 1.84 (1.44 to 2.36) | <0.001 |
Note: Values given as csHR (95% CI) for risk factors associated with ESRD and death prior to ESRD.
CCI, Charlson Comorbidity Index; CKD, chronic kidney disease; csHR, cause-specific HR; DM, diabetes mellitus; ESRD, end-stage renal disease; Hb, hemoglobin.