Control | FCH | p Value | |
N (M/F) | 36 (19/17) | 36 (17/19) | 0.427 |
Age (year) | 36.8±14.3 | 46.2±12.2 | 0.092 |
BMI | 26.9±5.4 | 27.4±3.7 | 0.337 |
Waist (cm) | 89.7±14.3 | 92.4±11.4 | 0.282 |
TC (mg/dL) | 197.1±24.4 | 267.5±29.5 | |
TG (mg/dL) | 96.7±43.8 | 190.8±140.9 | <0.001 |
HDL-C (mg/dL) | 55.8±12.9 | 56.8±13.8 | 0.714 |
LDL-C (mg/dL) | 122.2±24.5 | 177.2±25.2 | <0.001 |
ApoB (mg/dL) | 88.1±17.1 | 126.6±17.1 | <0.001 |
Glucose (mg/dL) | 88.1±10.5 | 99.0±14.1 | 0.001 |
Insulin (µU/mL) | 9.4±6.1 | 12.5±6.0 | 0.014 |
HOMA index | 2.08±1.40 | 3.15±1.87 | 0.006 |
MPO (ng/mL) | 38.8±158.2 | 92.8±234.3 | 0.664 |
PAI-1 (ng/mL) | 41.4±33.1 | 73.1±67.7 | 0.005 |
IMT (mm) | 0.47±0.12 | 0.55±0.11 | 0.013 |
Values expressed as mean±SD.
ApoB, apolipoprotein B; BMI, body mass index; FCH, familial combined hyperlipidemia; HDL-C, high density lipoprotein cholesterol; HOMA, homeostasis model assessment; IMT, intima media thickness; LDL-C, low density lipoprotein cholesterol; MPO, myeloperoxidase; N, number of subjects (M, males, F, females); PAI-1, plasminogen activator inhibitor type-1; TC, total cholesterol, TG, triglycerides; waist, abdominal circumference.