Table 5

Univariate and multivariate Cox analysis for composite events

ParametersHR (95% CI)p Value
Univariate analysis
 Age0.976 (0.952 to 1.034)0.857
 Hypertension (yes/no)0.815 (0.480 to 1.702)0.516
 Diabetes (yes/no)0.624 (0.261 to 1.664)0.410
 Vitamin D supplement (yes/no)0.382 (0.414 to 1.852)0.273
 FGF23 level (>503.2 or ≤503.2 pg/mL)0.391 (0.341 to 0.915)0.029
 s-Klotho level (>2.44 or ≤2.44 ng/mL)3.152 (1.446 to 7.807)0.013
 Ca (mmol/L)0.153 (0.026 to 1.322)0.082
 Phosphorus (mmol/L)4.329 (1.083 to 16.733)0.040
 iPTH (mmol/L)1.141 (1.083 to 1.226)0.268
 Albumin (g/L)0.954 (0.885 to 1.101)0.057
Multivariate analysis
 Phosphorus (mmol/L)3.159 (0.672 to 14.826)0.203
 FGF23 level (>503.2 or ≤503.2 pg/mL)1.316 (0.472 to 3.779)0.707
 s-Klotho level (>2.44 or ≤2.44 ng/mL)3.291 (1.056 to 9.823)0.048
  • Adjusted variables included in the model were: age, hypertension, vitamin D supplement, diabetes, FGF23 and Klotho levels, Ca, phosphorus, iPTH, and albumin.

  • Ca, calcium; FGF23, fibroblast growth factor 23; iPTH, intact parathyroid hormone.