Key presenting characteristics of two patients with EBV-HLH
| Labs at presentation | Patient A | Patient B |
|---|---|---|
| Age | 5 years | 15 months |
| Ethnicity | Hispanic | Native American |
| Liver/spleen | Splenomegaly | Hepatosplenomegaly |
| WBC (x10E3/uL) | 5.4 | 1.9 |
| Haemoglobin (g/dL) | 12.6 | 10.6 |
| Platelets (x10E3/uL) | 146 | 72 |
| PT(sec)/INR/aPTT(sec) | 13/1.12/42 | 15.5/1.33/37 |
| Fibrinogen (mg/dL) | 53 | 101 |
| D-dimer (ng/mL) | 20 267 | 21 367 |
| AST/ALT (Units/L) | 380/302 | 562/315 |
| Ferritin (ng/mL) | 26 619 | 6698 |
| LDH (Units/L) | NA | 2775 |
| Triglycerides (mg/dL) | 325 | 80 |
| Soluble IL-2R (Units/L) | 10 549 | Pending |
| EBV Titers (copies/mL) | 1 60 000 | >1,000,000 |
| CSF | Negative for hemophagocytosis | Cytology pending |
| MRI brain | Normal | Normal |