Table 3

Factors of injury among patients with dementia by using Cox regression

Variables	Crude HR	95% CI	P	Adjusted HR	95% CI	P	Adjusted HR	95% CI	P
Medications
(Reference: without)	0.206	0.195 to 0.217	<0.001	0.217	0.206 to 0.228	<0.001
Medications (days)
(Reference: 0)
1–364	0.249	0.221 to 0.269	<0.001				0.252	0.232 to 0.277	<0.001
≥365	0.198	0.145 to 0.219	<0.001				0.209	0.186 to 0.224	<0.001
Sex
Male
(Reference: female)	1.015	0.968 to 1.065	0.536	0.994	0.974 to 1.044	0.815	0.994	0.973 to 1.046	0.818
Age groups (years)
≥65
(Reference: 50–64)	0.761	0.641 to 0.904	0.002	0.751	0.632 to 0.893	0.001	0.750	0.634 to 0.895	0.002
Comorbidity
(Reference: without)
DM	0.828	0.779 to 0.879	<0.001	0.855	0.804 to 0.910	<0.001	0.855	0.806 to 0.911	<0.001
Hypertension	1.091	1.033 to 1.152	0.002	1.111	1.051 to 1.175	<0.001	1.112	1.050 to 1.176	<0.001
Hyperlipidemia	0.543	0.384 to 0.768	0.001	0.568	0.401 to 0.805	0.001	0.568	0.401 to 0.806	<0.001
CAD	0.639	0.581 to 0.703	<0.001	0.675	0.614 to 0.742	<0.001	0.677	0.618 to 0.747	<0.001
HF	0.404	0.353 to 0.462	<0.001	0.473	0.414 to 0.541	<0.001	0.472	0.415 to 0.543	<0.001
Obesity	6.864	0.966 to 48.534	0.054	2.021	0.284 to 14.372	0.482	2.019	0.265 to 13.397	0.479
Chronic kidney disease	0.640	0.578 to 0.710	<0.001	0.707	0.637 to 0.783	<0.001	0.708	0.640 to 0.787	<0.001
Depression	1.808	1.519 to 2.152	<0.001	1.676	1.407 to 1.996	<0.001	1.678	1.409 to 2.000	<0.001
Stroke	0.757	0.709 to 0.809	<0.001	0.752	0.704 to 0.804	<0.001	0.751	0.703 to 0.804	<0.001
Urbanization level
(Reference: 4)
1 (the highest)	0.775	0.723 to 0.831	<0.001	0.809	0.754 to 0.867	<0.001	0.808	0.754 to 0.872	<0.001
2	0.946	0.891 to 1.004	0.067	0.959	0.903 to 1.018	0.168	0.961	0.904 to 1.019	0.197
3	0.889	0.801 to 0.986	0.026	0.919	0.828 to 1.020	0.111	0.914	0.821 to 1.015	0.104
Geography
(Reference: Northern Taiwan)				Had collinearity with urbanization level			Had collinearity with urbanization level
Middle Taiwan	1.260	1.136 to 1.281	<0.001	Had collinearity with urbanization level			Had collinearity with urbanization level
Southern Taiwan	1.140	1.070 to 1.215	<0.001	Had collinearity with urbanization level			Had collinearity with urbanization level
Eastern Taiwan	1.343	1.234 to 1.461	<0.001	Had collinearity with urbanization level			Had collinearity with urbanization level
Outlets islands	0.957	0.640 to 1.431	0.831	Had collinearity with urbanization level			Had collinearity with urbanization level
Income (NT$)
(Reference:<18 000)
18 000–34 999	1.110	0.828 to 1.462	0.509	1.096	0.825 to 1.456	0.527	1.098	0.829 to 1.457	0.533
≥35 000	0	–	0.832	0	–	0.955	0	–	0.957

Adjusted HR: adjusted for sex, age, comorbidity, urbanization, geography, and income; CAD, coronary artery disease; DM, diabetes mellitus; HF, heart failure.