Table 2

The risk of irritable bowel syndrome compared with children without atopic dermatitis (AD) stratified by demographics in Cox proportional hazard regression

	Non- AD			AD
	Event	Person-years	IR	Event	Person-years	IR	Adjusted HR† (95% CI)
All	751	582 059	12.9	1094	583 428	18.8	1.45 (1.32 to 1.59)*
Stratified age
≤5	505	360 071	14.0	708	361 118	19.6	1.40 (1.25 to 1.57)*
6–11	148	164 053	9.02	230	164 268	14.0	1.55 (1.26 to 1.91)*
≥12	98	57 935	16.9	156	58 042	26.9	1.59 (1.23 to 2.05)*
Sex
Girl	308	264 049	11.7	494	264 609	18.7	1.60 (1.39 to 1.85)*
Boy	443	318 010	13.9	600	318 819	18.8	1.35 (1.19 to 1.53)*
Allergic rhinitis
No	657	518 043	12.7	834	436 145	19.1	1.50 (1.35 to 1.66)*
Yes	94	64 016	14.7	260	147 283	17.7	1.21 (0.96 to 1.54)
Asthma
No	709	545 153	13.0	945	486 037	19.4	1.49 (1.35 to 1.64)*
Yes	42	36 906	11.4	149	97 391	15.3	1.35 (0.96 to 1.90)

*p<0.001.
Adjusted HR†, adjusted for age and sex.
IR, incidence rate, per 10 000 person-years.