Table 2

Univariate and multivariate Cox hazard regression for risk of overall mortality and cancer-specific mortality in primary cutaneous T-cell lymphoma

VariableOverall mortalityCancer-specific mortality
HR (95% CI)P valueaHR (95% CI)P valueHR (95% CI)P valueaHR (95% CI)P value
Case
 Non-HIVReferenceReferenceReferenceReference
 HIV 0.39 (0.27 to 0.58) <0.001  0.37 (0.24 to 0.59) <0.001 0.33 (0.19 to 0.58) <0.001 0.29 (0.15 to 0.56) <0.001
Age 1.04 (1.03 to 1.05) <0.001 1.04 (1.03 to 1.05) <0.001 1.02 (1.01 to 1.03) <0.001 1.02 (1.01 to 1.03) <0.001
Gender
 MaleReferenceReferenceReferenceReference
 Female0.84 (0.66 to 1.07)0.1480.85 (0.64 to 1.12)0.2470.95 (0.69 to 1.31)0.7630.94 (0.65 to 1.37)0.752
Race/ethnicity
 WhiteReferenceReferenceReferenceReference
 Black0.99 (0.70 to 1.42)0.966 1.57 (1.05 to 2.34) 0.029 0.82 (0.49 to 1.36)0.4421.39 (0.80 to 2.41)0.249
 Asian or Pacific Islander1.1 (0.69 to 1.75)0.6871.37 (0.76 to 2.47)0.2921.47 (0.85 to 2.54)0.1641.42 (0.72 to 2.79)0.314
 Others* 0.37 (0.17 to 0.82) 0.015 0.46 (0.11 to 1.97)0.2960.36 (0.12 to 1.08)0.5320.33 (0.05 to 2.39)0.271
Marital status at diagnosis
 Single†ReferenceReferenceReferenceReference
 Married0.85 (0.67 to 1.09)0.1950.85 (0.65 to 1.13)0.2670.92 (0.66 to 1.28)0.6200.92 (0.63 to 1.33)0.654
Region of SEER registry
 WestReferenceReferenceReferenceReference
 South1.16 (0.80 to 1.66)0.4360.96 (0.63 to 1.46)0.8440.91 (0.54 to 1.51)0.7010.79 (0.43 to 1.47)0.454
 North Central0.86 (0.61 to 1.22)0.4030.70 (0.48 to 1.03)0.072 0.50 (0.28 to 0.89) 0.018 0.50 (0.26 to 0.94) 0.033
 Northeast0.76 (0.46 to 1.24)0.2671.13 (0.69 to 1.85)0.6420.88 (0.49 to 1.58)0.6701.21 (0.66 to 2.21)0.537
Treatments
 No treatment‡ReferenceReferenceReferenceReference
 With treatment§1.24 (0.94 to 1.64)0.1260.99 (0.75 to 1.34)0.9951.06 (0.72 to 1.57)0.7620.88 (0.58 to 1.30)0.499

  • Bold text indicates a statistically significant difference with P<0.05.

  • *Including American Indian, Alaska Native, other unspecified, and unknown.

  • †Including single, separated, divorced, and widowed.

  • ‡Including no surgery or no radiotherapy as provided by the SEER database. Other modality of treatment was unknown.

  • §Including surgery or radiotherapy.

  • SEER, Surveillance, Epidemiology, and End Results.