Association of changes in CTC parameters with HCC recurrence in groups 1 and 2
| Total | Group 1 | Group 2 | |||||||
| Recurrence (n=15) | No recurrence (n=32) | p Values | Recurrence (n=3) | No recurrence (n=17) | p Values | Recurrence (n=12) | No recurrence (n=15) | p Values | |
| CTC count—total | 0.514 | 0.270 | 0.823 | ||||||
| Reduction | 7 (46.7) | 19 (59.4) | 0 (0) | 9 (53.0) | 7 (58.3) | 10 (66.7) | |||
| Stability | 1 (6.6) | 4 (12.5) | 1 (33.3) | 3 (17.5) | 0 (0) | 1 (6.6) | |||
| Increase | 7 (46.7) | 9 (28.1) | 2 (66.7) | 5 (29.4) | 5 (41.7) | 4 (26.7) | |||
| CTC count—epithelial | 0.926 | 0.393 | 0.379 | ||||||
| Reduction | 4 (26.7) | 11 (34.4) | 0 (0) | 4 (23.5) | 4 (33.3) | 7 (46.7) | |||
| Stability | 6 (40.0) | 11 (34.4) | 1 (33.3) | 9 (53.0) | 5 (41.7) | 2 (13.3) | |||
| Increase | 5 (33.3) | 10 (31.2) | 2 (66.7) | 4 (23.5) | 3 (25.0) | 6 (40.0) | |||
| CTC count—mixed | 0.818 | 1.000 | 0.821 | ||||||
| Reduction | 9 (60) | 20 (62.4) | 2 (66.7) | 9 (53.0) | 7 (58.3) | 11 (73.3) | |||
| Stability | 2 (13.3) | 6 (18.8) | 1 (33.3) | 5 (29.4) | 1 (8.3) | 1 (6.7) | |||
| Increase | 4 (26.7) | 6 (18.8) | 0 (0) | 3 (17.6) | 4 (33.3) | 3 (20.0) | |||
| CTC count—interstitial | 0.726 | 0.768 | 0.131 | ||||||
| Reduction | 3 (20) | 11 (34.4) | 1 (33.3) | 3 (17.6) | 2 (16.7) | 8 (53.3) | |||
| Stability | 7 (46.7) | 12 (37.5) | 1 (33.3) | 9 (53.0) | 6 (50) | 3 (20.0) | |||
| Increase | 5 (33.3) | 9 (28.1) | 1 (33.3) | 5 (29.4) | 4 (33.3) | 4 (26.7) | |||
Data were summarized as n (%) and analyzed using Fisher’s exact test.
CTC, circulating tumor cell; HCC, hepatocellular carcinoma.