Effect of statins in different cancer therapy strategies
| Type of cancer | Major findings |
| ER-negative breast cancer (stage I breast cancer) | Using fluvastatin (80 mg/day) for 3–6 weeks before surgery decreased tumor proliferation and increased tumor apoptosis in only high-grade tumor78 |
| Glioblastoma multiform | Long-term prediagnostic statin (simvastatin) use may improve survival following glioblastoma multiform6 |
| Extensive-disease small-cell lung cancer | The addition of simvastatin (40 mg daily) to irinotecan and cisplatin may improve the outcome of heavy smokers extensive-disease small-cell lung cancer79 |
| Small-cell lung cancer | Pravastatin 40 mg combined with standard small-cell lung cancer therapy, although safe, does not benefit patients80 |
| Prostate cancer | Using statins decreased advance prostate cancer risk81 |
| Brain metastasis tumors | The addition of simvastatin 80 mg/day did not improve the clinical outcomes of patients with brain metastasis receiving whole-brain radiation therapy82 |
| Different types of cancers | Patients aged 45 years or more and discharged from the hospital alive after admission for acute myocardial infarction after using high dose of statins show lower risk of cancers83 |