Types of expression and localization | ||||
Desmin | ||||
Type | I | IIA | IIB | III |
Localization | Cytoplasm | Cytoplasm | Cytoplasm | Cytoplasm |
Expression | Even, weak | Intensive | Intensive, aggregates | Weak/absent |
Ubiquitin | ||||
Type | A | B | C | D |
Localization | Cytoplasm | Cytoplasm | Cytoplasm and nucleus | Cytoplasm |
Expression | Even, weak | Intensive | Intensive | Weak/absent |
Desmin mRNA | ||||
Type | 1 | 2 | 3 | 4 |
Localization | Cytoplasm and nucleus | Cytoplasm and nucleus | Cytoplasm and nucleus | Cytoplasm |
Expression | Even, weak | Uneven, and mainly in the nucleus | Even, intensive | Weak/absent |
IDCM, idiopathic dilated cardiomyopathy.