| Variable | Epoch 1 (2013–2015) | Epoch 2 (2017) | p value |
|---|---|---|---|
| Total number of births at participating institutions | 10,97,799 | 3,60,423 | |
| Incidence of MAS requiring NICU admission among total live births at participating institutions | 1379 (0.126%) | 402 (0.112%) | <0.0001 |
| Incidence of MAS among all NICU admissions≥36 weeks gestation | 7.45% | 5.86% | <0.0001 |
| Delivery room intubations | 499/1378* (36.2%) | 109/400* (27.3%) | 0.0009 |
| Post DR – any type of intubated respiratory support | 375/1379 (27.2%) | 111/402 (27.6%) | 0.87 |
| Post DR- High frequency ventilation | 384/1377* (27.9%) | 101/402 (25.1%) | 0.27 |
| Use of Inhaled Nitric oxide | 299/1379 (21.8%) | 97/402 (24.1%) | 0.32 |
| ECMO | 34/1379 (2.5%) | 5/402 (1.2%) | 0.18 |
| Pneumothorax | 162/1379 (11.8%) | 50/402 (12.4%) | 0.7 |
| Moderate/Severe HIE | 138/1362* (10.1%) | 46/400* (11.5%) | 0.43 |
*values missing in some subjects