Comparison of surgical and non-surgical management of epilepsy in children
| 1st Author, Year | Subject (n) in Surgery Group | Control (n) in Non-Surgery Group | Age at Surgery (years) | Localization of Seizures | % Seizure Free: Surgical vs. Non-Surgical | Follow-Up Time (years) |
|---|---|---|---|---|---|---|
| Dwivedi, 2017 | 57 | 59 | ≤18 | Temporal: 24.6% Extra-Temporal: 75.4% | 77% vs. 7% (p<0.001) | 1 |
| Puka, 2016 | 71 | 37 | 12.98 (Mean) | Temporal: 53.85% Extra-Temporal: 46.2% | 92.8% vs. 57% (p=0.001) | 6.98 (Mean) |
| Otsuki, 2015 | 31 resective surgery 36 palliative surgery | 250 | <6 | All Extratemporal | Surgical 52.4% Palliative 32.1% Medical 15.7% | 3 |
| Edelvik, 2013 | 88 | 13 | ≤18 | Temporal: 43% Extra-Temporal: 57% | 44.0% vs. 0.00% (p<0.0005) | 10 |
| Mikati, 2010 | 19 | 19 | 2–14 | Temporal: 36.8% Extra-Temporal: 63.2% | 78.9% vs. 21.1% (p=0.01) | 3.44–3.84 (Mean) |
| Skirrow, 2010 | 42 | 11 | 12.3–13.3 (Mean) | All Temporal | 86.0% vs. 36.0% (p=0.002) | 9 |
| Rausch, 2003 | 44 | 8 | Not Stated | Left Side: 47.7% Right Side: 52.3% | 88% of non-surg and 50% of surg had at least one seizure (p<0.05) | 12 |