Clinical characteristics of patients with acute ischemic stroke
| Clinical characteristics | All patients | Patients in good prognosis | Patients in poor prognosis | P value |
| n=772 | n=576 | n=196 | ||
| Age | 66.1±12.8 | 64.0±12.5 | 72.5±11.3 | <0.001 |
| ≥70 | 341 (44.2%) | 210 (36.5%) | 131 (66.8%) | <0.001 |
| Male | 536 (69.4%) | 413 (71.7%) | 123 (62.8%) | 0.019 |
| Preadmission dependency | 48 (6.2%) | 15 (2.6%) | 33 (16.8%) | <0.001 |
| History of smoking | 362 (46.9%) | 286 (49.7%) | 76 (38.8%) | 0.008 |
| History of drinking | 243 (31.5%) | 201 (34.9%) | 42 (21.4%) | <0.001 |
| NIHSS score | <0.001 | |||
| <9 | 628 (81.3%) | 529 (91.8%) | 99 (50.5%) | <0.001 |
| 9–13 | 93 (12.0%) | 40 (6.9%) | 53 (27.0%) | <0.001 |
| 14–22 | 34 (4.4%) | 4 (0.7%) | 30 (15.3%) | <0.001 |
| >22 | 17 (2.2%) | 3 (0.5%) | 14 (7.1%) | <0.001 |
| Median score | 3 (1.25, 6) | 2 (1, 5) | 8 (4, 13) | <0.001 |
| TOAST classification | ||||
| Large-artery atherosclerosis | 396 (51.3%) | 301 (52.3%) | 95 (48.5%) | 0.359 |
| Cardioembolism | 44 (5.7%) | 17 (3.0%) | 27 (13.8%) | <0.001 |
| Small-vessel occlusion | 127 (16.5%) | 116 (20.1%) | 11 (5.6%) | <0.001 |
| Stroke of other determined or undetermined etiology | 205 (26.6%) | 142 (2.1%) | 63 (32.1%) | 0.04 |
| Level of consciousness | ||||
| Drowsiness or lethargy or coma | 74 (9.6%) | 15 (2.6%) | 59 (30.1%) | <0.001 |
| Risk factors | ||||
| History of stroke or TIA | 259 (33.5%) | 158 (27.4%) | 101 (51.5%) | <0.001 |
| Cerebral infarction | 225 (29.1%) | 139 (24.1%) | 86 (43.9%) | <0.001 |
| Cerebral hemorrhage | 27 (3.5%) | 12 (2.1%) | 15 (7.7%) | 0.001 |
| TIA | 14 (1.8%) | 7 (1.2%) | 7 (3.6%) | 0.056 |
| Hypertension | 509 (65.9%) | 371 (64.4%) | 138 (70.4%) | 0.126 |
| History of hypertension >7 years | 337 (43.7%) | 229 (39.8%) | 108 (55.1%) | <0.001 |
| Diabetes | 261 (33.8%) | 187 (32.5%) | 74 (37.8%) | 0.176 |
| Hyperlipidemia | 128 (16.6%) | 99 (17.2%) | 29 (14.8%) | 0.437 |
| Coronary heart disease | 141 (18.3%) | 93 (16.1%) | 48 (24.5%) | 0.009 |
| Myocardial infarction | 30 (3.9%) | 18 (3.1%) | 12 (6.1%) | 0.061 |
| Atrial fibrillation | 76 (9.8%) | 39 (6.8%) | 37 (18.9%) | <0.001 |
| Chronic heart failure | 12 (1.6%) | 6 (1.0%) | 6 (3.1%) | 0.048 |
| Peripheral arterial disease | 5 (0.6%) | 2 (0.3%) | 3 (1.5%) | 0.074 |
| Dementia | 10 (1.3%) | 3 (0.5%) | 7 (3.6%) | 0.004 |
| Cancer | 28 (3.6%) | 11 (1.9%) | 17 (8.7%) | <0.001 |
| Renal dialysis | 3 (0.4%) | 1 (0.2%) | 2 (1.0%) | 0.100 |
| Fasting blood glucose (mmol/L) | ||||
| ≥7.0 | 342 (44.3%) | 235 (40.8%) | 107 (54.6%) | 0.001 |
| Glycated hemoglobin | ||||
| ≥6.5% | 532 (68.9%) | 409 (71.0%) | 123 (77.2%) | 0.031 |
NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischemic attack.