Table 1

A comparison of observed minus expected outcomes in relation to cause-specific mortality (data sourced from Ridker et al 7)

Cause of deathDeaths in placebo*
(n=3344 total)
Death in treated
(n=6717 total)
Expected deaths†Observed-expected
(difference [%])
Lung cancer383977−38 (−49)
Other cancers437686−10 (−12)
Sepsis237846+32 (+70)
Cardiovascular182319366−47 (−13)
Other/unknown89193178+15 (+8)
  • †The absolute number of expected deaths in the treated arm were calculated according to deaths in the placebo arm*. These were estimated to be approximately twofold that in the placebo arm.7