Table 2
Conditions associated with changes in the concentration of SHBG
| Increased | Decreased |
| Aging Hyperthyroidism Use of estrogens Chronic liver diseases HIV (+) status Thiazolidinedione use Anticonvulsant use Smoking Polymorphisms in the SHBG gene | Obesity/diabetes mellitus/metabolic syndrome Nephrotic syndrome Hypothyroidism Acromegaly Androgen, progestin, or glucocorticoid use Polymorphisms in the SHBG gene |
TT, but not FT increased |
TT, but not FT decreased |