Miscellaneous association of RS3PE
| Case | Treatment | Recommendation | |
| 1 | RS3PE during course of toxic shock syndrome (TSS) | Steroids | An increase in serum VEGF due to TSS might trigger RS3PE syndrome. |
| 2 | Bilateral pleural and pericardial effusions during the course of the illness leading to respiratory failure and atrial fibrillation | Intravenous methylprednisolone 1000 mg/day for 3 days | Elevated VEGF and IL-6 may be associated with the underlying cause of pleural and pericardial effusions in this case. |
| 3 | RS3PE associated with iliopsoas bursitis | Oral corticosteroids | Iliopsoas bursitis in a patient with RS3PE syndrome may resemble an iliopsoas abscess on MRI. |
| 4 | RS3PE with additional dermatological manifestations | Prednisone | An increased awareness of RS3PE syndrome among dermatologists may be warranted. |
| 5 | RS3PE after dipeptidyl peptidase-4 (DPP-4) inhibitor use | Discontinuation of the agent Corticosteroids | Awareness of the association of RS3PE as an adverse effect of DPP-4 inhibitors is warranted. |
| 6 | RS3PE with rifampicin use | Discontinuation of rifampicin | A possible direct etiological link between rifampicin and RS3P may exist. |
IL, interleukin; RS3PE, remitting seronegative symmetrical synovitis with pitting edema; VEGF, vascular endothelial growth factor.