Parameter | Preoperative | 1 month | 3 month | 6 month | 12 month | Mean difference | P value | Between-group difference at 12 months (mean difference (95% CI)) | P value for difference in means between groups at 12 months | |
SBP (mm Hg) | RYGB | 133.4 (16) | 124.9 (16) | 127.4 (15.8) | 125.1 (19.1) | 124.5 (17.1) | 8.9 (3) | 0.003 | −4.6 (−9.5 to 0.3) | 0.07 |
SG | 132.2 (18.3) | 124.2 (16.5) | 127.3 (15.3) | 123.0 (15.7) | 129.1 (15.1) | 3.1 (3.2) | 0.34 | |||
DBP (mm Hg) | RYGB | 80.2 (11.4) | 74.9 (11.6) | 76.7 (11.1) | 76.3 (10.8) | 72.5 (8.4) | 7.7 (1.9) | <0.001 | −4.2 (−7.1 to −1.3) | 0.01 |
SG | 80.4 (12.3) | 76.2 (10.4) | 76.5 (9.1) | 74.2 (10.9) | 76.7 (10.5) | 3.7 (2.2) | 0.08 | |||
HR (beats/min) | RYGB | 81.4 (13.4) | 76.3 (12) | 73.5 (11.1) | 70.6 (11.2) | 73.1 (12.1) | 8.2 (2.4) | 0.001 | 2.4 (−1.2 to 6) | 0.2 |
SG | 80.3 (12.9) | 77.2 (14.3) | 71.5 (13.8) | 69 (11.9) | 70.7 (11.4) | 9.6 (2.3) | <0.001 | |||
Weight (kg) | RYGB | 134.2 (36.5) | 121.5 (34.6) | 110.4 (33.4) | 99.1 (31) | 86.7 (24.9) | 47.5 (6) | <0.001 | −2.3 (−9.3 to 4.7) | 0.5 |
SG | 130.7 (30.3) | 117.2 (26.1) | 109 (27.2) | 100.5 (25.7) | 89.0 (21.3) | 41.7 (5.1) | <0.001 | |||
BMI (kg/m2) | RYGB | 47.5 (10.6) | 43 (10.1) | 39.1 (10.4) | 35.1 (9) | 30.7 (7) | 16.8 (1.7) | <0.001 | −0.9 (−2.9 to 1.1) | 0.4 |
SG | 46.8 (9.1) | 41.8 (7.8) | 39.1 (8.0) | 35.8 (7.6) | 31.6 (6.1) | 15.2 (1.5) | <0.001 | |||
BP meds | RYGB | 1.5 (1.4) | 0.8 (1.1) | 0.6 (1) | 0.7 (1.1) | 0.5 (0.9) | 0.9 (0.2) | <0.001 | NA | 1 |
SG | 1.6 (1.3) | 0.6 (0.8) | 0.7 (0.9) | 0.5 (0.8) | 0.5 (0.8) | 1 (0.2) | <0.001 |
Mean difference: mean change within subjects from baseline (presurgery) to follow-up (12 months).
P value for baseline to 12 months of follow-up mean difference (two-tailed).
Continuous variables described as absolute means (SD). Mean difference reported with SE in parentheses.
BMI, body mass index; BP, blood pressure; DBP, diastolic blood pressure; HR, heart rate; NA, not applicable; RYGB, Roux-en-Y gastric bypass; SBP, systolic blood pressure; SG, sleeve gastrectomy.