All, n=90 (%) | AS-Present, n=19 (%) | AS-Absent, n=71 (%) | P-value | |
---|---|---|---|---|
Age, years | 64.2 ± 1.1 | 66.3 ± 2.2 | 63.7 ± 1.3 | 0.33 |
Gender (female) | 62 (68.9) | 10 (52.6) | 52 (73.2) | 0.10 |
BMI, kg/m2 | 26.6 ± 0.6 | 27.1 ± 1.2 | 26.5 ± 0.7 | 0.69 |
Diabetes Mellitus | 14 (15.6) | 0 (0) | 14 (19.7) | 0.04* |
Hypertension | 50 (55.6) | 13 (68.4) | 37 (52.1) | 0.29 |
Coronary Artery Disease | 20 (22.2) | 6 (31.6) | 14 (19.7) | 0.35 |
Dyslipidemia | 41 (45.6) | 10 (52.6) | 31 (43.7) | 0.61 |
Chronic Obstructive Pulmonary Disease | 11 (12.2) | 4 (21.0) | 7 (9.9) | 0.24 |
Smoker (>10 pack years) | 41 (45.6) | 11 (57.9) | 30 (42.3) | 0.30 |
Chronic Kidney Disease | 18 (20.0) | 5 (26.3) | 13 (18.3) | 0.52 |
Scleroderma Type | ||||
Limited Cutaneous | 72 (80.0) | 17 (89.5) | 55 (77.5) | 0.34 |
Diffuse Cutaneous | 12 (13.3) | 1 (5.3) | 11 (15.5) | 0.45 |
Overlap Syndrome | 4 (4.4) | 0 (0.0) | 4 (5.6) | 0.58 |
Sine | 2 (2.2) | 1 (5.3) | 1 (1.4) | 0.38 |
Scleroderma Manifestations | ||||
Telangiectasias | 82 (91.1) | 18 (94.7) | 64 (90.1) | 0.99 |
Raynaud’s phenomenon | 88 (97.8) | 18 (94.7) | 70 (98.6) | 0.38 |
Sclerodactyly | 76 (84.4) | 17 (89.5) | 59 (83.1) | 0.73 |
Calcinosis Cutis | 29 (32.2) | 7 (36.8) | 22 (30.1) | 0.78 |
GERD | 71 (78.9) | 13 (68.4) | 58 (81.7) | 0.22 |
Antibody Profile | ||||
Anti-Centromere | 36 (40.0) | 9 (47.4) | 27 (30.0) | 0.60 |
SCl-70 | 11 (12.2) | 1 (5.3) | 10 (14.1) | 0.45 |
SSB or SSA | 10 (11.1) | 1 (5.3) | 9 (12.7) | 0.68 |
Rheumatoid Factor | 9 (10.0) | 1 (5.3) | 8 (11.3) | 0.68 |
RNA Polymerase II | 1 (1.1) | 0 (0) | 1 (1.4) | 0.99 |
Anti-U1-RNP | 3 (3.3) | 0 (0) | 3 (4.2) | 0.99 |
Interstitial Lung Disease | 36 (40.0) | 7 (36.8) | 29 (40.8) | 0.80 |
*Statistically significant at p<0.05, the unpaired t-test with Welch’s correction was used for continuous variables and the Fischer-exact test was used for categorical variables. Variance= standard error