Multivariate Cox regression analysis of the correlation between EphA10/Gli3 expression and the overall survival of patients with invasive BC
| CPC | P value | Relative risk | 95% CI | ||
| Lower | Upper | ||||
| Age (years) | ≤45/>45 | 0.029 | 2.291 | 1.088 | 4.823 |
| Menopausal status | Prememopausal /prememopausal | 0.061 | 2.032 | 0.968 | 4.265 |
| Tumor size | ≤3 cm/>3 cm | 0.028 | 1.859 | 1.070 | 3.228 |
| Histologic grade | Ⅰ/Ⅱ/Ⅲ | 0.000 | 3.543 | 2.213 | 5.673 |
| Lymph node metastasis | No/yes | 0.020 | 2.521 | 1.158 | 5.490 |
| TNM stage | I/II/III/IV | 0.004 | 1.948 | 1.235 | 3.074 |
| ER | −/+ | 0.568 | 0.797 | 0.366 | 1.735 |
| PR | −/+ | 0.215 | 0.602 | 0.269 | 1.344 |
| CerB2 | −/+ | 0.988 | 1.004 | 0.627 | 1.606 |
| EphA10 | −/+ | 0.001 | 2.515 | 1.473 | 4.293 |
| Gli3 | −/+ | 0.009 | 1.940 | 1.180 | 3.189 |
BC, breast cancer; CI, confidence interval; CPC, clinicopathological characteristics; ER, estrogen receptor; PR, progesterone receptor; TNM, tumor, node, metastasis.