Multivariate logistic regression analysis for PAD associated with independent effect of eGFR and ACR
| Variable | Model I | Model II | ||
| OR 95% CI | P value | OR 95% CI | P value | |
| eGFR stage | ||||
| eGFR ≥90 | 1 (reference) | 1 (reference) | ||
| eGFR 60–89 | 2.52 (1.23 to 5.16) | 0.012 | 2.41 (1.17 to 4.96) | 0.017 |
| eGFR <30–59 | 4.24 (2.00 to 9.00) | <0.001 | 3.69 (1.73 to 7.88) | 0.001 |
| eGFR <30 | 6.40 (2.41 to 17.03) | <0.001 | 5.39 (2.00 to 14.48) | 0.001 |
| ACR category | ||||
| <30 | 1 (reference) | |||
| 30–299 | 1.57 (0.91 to 2.71) | 0.100 | 1.37 (0.79 to 2.39) | 0.260 |
| >300 | 2.83 (1.55 to 5.17) | 0.001 | 2.29 (1.24 to 4.25) | 0.008 |
| Age | 1.03 (1.01 to 1.06) | 0.017 | NS | |
| Hypertension | 2.78 (1.42 to 5.45) | 0.003 | 2.16 (1.18 to 3.96) | 0.012 |
| Coronary artery disease | 2.77 (1.49 to 5.14) | 0.001 | 2.60 (1.48 to 4.56) | 0.001 |
Model I: univariate analysis, and model II: adjusted for age, hypertension, coronary artery disease and other variables included: gender, DM duration, smoking, hyperlipidemia and HbA1c.
ABI, ankle-brachial index; ACR, albumin-to-creatinine ratio; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; NS, not significant; PAD, peripheral arterial disease.