Characteristics | NSTI, n=80 |
Age (years) | 61 (52—68) |
Sex, male | 52 (65) |
BMI (kg/m2) | 26 (24—31) |
Comorbidities | |
Cardiovascular disease | 35 (44) |
Chronic kidney disease | 5 (6) |
COPD | 6 (8) |
Diabetes | 21 (26) |
Immune deficiency | 2 (3) |
Liver cirrhosis | 1 (1) |
Malignancy | 7 (9) |
Peripheral vascular disease | 11 (14) |
Rheumatoid disease | 4 (5) |
Polyicrobial versus monomicrobial | |
Monomicrobial infections | 30 (37) |
Polymicrobial infections | 42 (53) |
Negative findings | 8 (10) |
Biochemistry | |
Leukocyte count (109/L) | 15 (10–22) |
C reactive protein (mg/L) | 221 (148–324) |
Creatinine (µmol/L) | 109 (78–181) |
Lactate (mmol/L) | 2.3 (1.3–3.3) |
Other | |
SOFA score* | 8 (6–10) |
SAPS II† | 44 (35–51) |
LRINEC‡ | 8 (7–10) |
Septic shock on admission§ | 39 (49) |
Amputation within 7 days | 13 (16) |
RRT within 7 days | 12 (15) |
Mortality, day 90 | 12 (15) |
Continuous data are presented as medians (IQR) and categorical data as absolute numbers (percentage, %).
*SOFA score, day 1; data were missing for three (4%) patients.
†Data were missing for three (4%) patients.
‡Data were missing for eight (10%) patients.
§Septic shock defined as lactate>2 mmol/L and use of vasopressor or inotrope.
BMI, Body Mass Index; COPD, chronic obstructive pulmonary disease; LRINEC, Laboratory Risk Indicator for Necrotizing Fasciitis Score; NSTI, necrotizing soft-tissue infection; RRT, renal-replacement therapy; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment.