Distribution of oxygenation requirement, level of care unit and outcomes according to baseline magnesium levels
| Total | Normomagnesemia Mg <2.5 | Hypermagnesemia Mg ≥2.5 | P value | |
| Oxygenation*, n (%) | ||||
| Nasal cannula | 54 | 29 (33) | 25 (24) | 0.18 |
| Ventilator | 35 | 1 (1.12) | 34 (33) | <0.0001 |
| Other† | 59 | 26 (29) | 33 (32) | 0.71 |
| Therapy, n (%) | ||||
| Remdesivir | 75 | 29 (33) | 46 (45) | 0.09 |
| Dexamethasone | 134 | 46 (52) | 88 (85) | <0.0001 |
| Convalescent plasma | 120 | 52 (58) | 68 (65) | 0.32 |
| Level of care unit and outcomes‡, n (%) | ||||
| MedSurg | 132 | 76 (85) | 56 (54) | <0.001 |
| ICU | 61 | 13 (15) | 48 (46) | <0.001 |
| Death | 24 | 6 (7) | 18 (17) | 0.03 |
| Days in hospital | 87 | 6.7 (4) | 15.42 (13) | 0.001 |
| Days in ICU | 40 | 6.18 (5) | 14.55 (11) | 0.03 |
| Logistic regression analysis§ | ||||
| Univariate OR (95% CI) | P value | Multivariable adjusted OR (95% CI) | P value | |
| Death | 2.89 (1.10 to 7.65) | 0.03 | 5.39 (1.59 to 18.28) | 0.007 |
Χ2 and Fisher’s exact tests were used for categorical variables. Total n represents available data from all patients.
Results displayed in bold highlight the requirement of ventilator and outcomes which reached statistical significance.
*A p value <0.05 is used for statistical significance. T-test is used for comparison of continuous variables.
†Other is defined as use of high-flow nasal cannula, respiratory mask and bilevel positive airway pressure (BiPAP).
‡A p value <0.05 is used for statistical significance. Multivariable model adjusted for age, gender, race and overall comorbidity burden (sum of 8 comorbidities above).
§Death (outcome) was assessed from chart review. Age-adjusted analysis using logistic regression analysis (age at admission).
ICU, intensive care unit; MedSurg, (medical-surgical) admission into the inpatient unit.