Table 1

Demographic and baseline characteristics

	Exenatide group			Insulin group
	Normal N=17	Overweight and obese N=10	P value	Normal N=15	Overweight and obese N=17	P value
Age, years	60.47±10.88	56.1±15.21	0.391	61.73±9.83	58.76±10.06	0.414
HbA1c, %	8.54±1.03	8.89±1.07	0.412	8.4±0.77	8.26±1.13	0.702
FPG, mmol/L	9.92±2.92	11.17±2.99	0.315	11.34±2.56	10.35±2.47	0.285
eGFR, mLl/min/1.73 m²	100.9±12.32	105.8±14.18	0.375	101.3±11.02	104.5±11.72	0.442
BMI, kg/m²	21.82±1.27	26.75±1.97	<0.0001	22.18±1.44	26.29±1.48	<0.0001
SBP, mm Hg	123.8±17.19	132.5±14.39	0.196	126.7±16.87	124.4±13.68	0.683
DBP, mm Hg	80.29±10.07	80±9.43	0.947	73.33±9	76.76±9.18	0.370
TBIL, mmol/L	12.63±4.75	10.99±4.54	0.393	10.71±2.78	11.8±5.08	0.463
DBIL, mmol/L	3.87±1.59	3.85±1.91	0.983	3.34±0.74	3.66±1.79	0.537
TG, mmol/L	2.27±1.76	2.05±0.99	0.724	2±1.48	2.2±1.55	0.713
TC, mmol/L	4.89±1.49	4.35±1.25	0.342	4.7±0.91	4.56±0.83	0.658
LDL, mmol/L	3.11±1.03	2.87±1.12	0.581	2.8±0.87	2.85±0.65	0.860
HDL, mmol/L	1.07±0.25	1.06±0.41	0.942	1.18±0.22	1.11±0.26	0.412
FIB, g/L	2.89±0.68	2.88±0.64	0.965	2.98±0.25	2.87±0.71	0.543
Irisin, pg/mL	71.04±5.9	73.75±4.66	0.252	71.36±5.09	70.09±5.95	0.551
8-oxo-Gsn, ng/mL	6.58±0.55	6.65±0.42	0.701	6.68±0.71	6.52±0.67	0.574
NT-proBNP, pg/mL	220.2±25.5	202.9±19.18	0.110	218.5±25.17	207.7±23.49	0.250
IMT, mm	1.01±0.216	1.04±0.28	0.784	1.22±0.12	1.04±0.25	0.051

BMI, body mass index; DBIL, direct bilirubin; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FIB, fibrinogen; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; IMT, intima media thickness; LDL, low-density lipoprotein; NT-proBNP, N-terminal pro-brain natriuretie peptide; 8-oxo-Gsn, 8-oxo-7,8-dihydroguanosine; SBP, systolic blood pressure; TBIL, total bilirubin; TC, total cholesterol; TG, triglyceride.