Table 3

Frequency of symptoms before and after treatment with high-dose domperidone

SymptomPretreatment average frequencyPost-treatment average frequencyPercentage decreaseP value
Abdominal pain3.33 (1.19)1.38 (1.36)58.56<0.001
Early satiety3.43 (1.12)1.71 (1.71)50.15<0.001
Bloating2.90 (1.45)2.24 (1.48)22.760.095
Nausea3.14 (1.32)1.52 (1.50)51.59<0.001
Vomiting2.19 (1.72)0.52 (1.03)76.26<0.001
Constipation1.62 (1.72)0.90 (1.22)44.440.052
Diarrhea1 (1.18)0.81 (1.25)190.463
  • Symptom frequency was graded on a 5-point Likert scale ranging from 0 to 4 (0=absent; 1=once a week; 2=two to three times a week; 3=four to six times a week; 4=daily or more).