Table 3

Univariate and logistic regression analysis of the timing of convalescent plasma administration with 28-day mortality as the dependent outcome

n (%)28-day mortality
100/patients
Unadjusted
OR (95%CI)
Adjusted (model 1)
OR (95% CI)
Adjusted (model 2)
OR (95% CI)
>7 days226 (4.8)38.9111
3–7 days1380 (29.2)30.40.68 (0.51 to 0.92)0.75 (0.55 to 1.02)0.46 (0.33 to 0.62)
<3 days3113 (66.0)18.10.35 (0.263 to 0.46)0.39 (0.29 to 0.52)0.81 (0.59 to 1.12)
  • Model 1: adjusted for age, gender, obesity, diabetes, hypertension, cardiovascular disease, chronic obstructive pulmonary disease and immunodeficiencies.

  • Model 2: model 1 plus initial severity of illness assessed according to the hospital site of admission: general ward, intensive care unit (ICU), and ICU admission with requirement of mechanical ventilation.