Clinical materials in 8 patients with concomitant AMI and acute ICH
| Case | Age (years) and gender | Traditional risk factors | PCI after AMI | Blood tests | Coagulation functions | Plasma lipid |
| 1 | Female in her 70s | Hypertension | No | PLT 161 HB 100 | PT 15.20 APTT 36.10 TT 17.30 INR 1.22 FIB 3.03 D-dimer 7.50 | Cholesterol 3.79 Triglyceride 0.80 HDL 1.21 LDL 1.33 |
| 2 | Male in his 60s | Hypertension, diabetes mellitus, a history of AIS, smoking | Yes | PLT 109 HB 136 | PT 12.60 APTT 40.70 TT 16.70 INR 0.96 FIB 3.41 D-dimer 1.17 | Cholesterol 3.68 Triglyceride 0.87 HDL 1.21 LDL 2.30 |
| 3 | Male in his 50s | Smoking | Yes | PLT 596 HB 119 | PT 12.80 APTT 35.30 TT 18.30 INR 0.96 FIB 2.16 D-dimer 0.25 | Cholesterol 5.59 Triglyceride 2.68 HDL 0.92 LDL 2.04 |
| 4 | Male in his 60s | Hypertension, smoking | Yes | PLT 173 HB 136 | PT 14.60 INR 1.16 | Cholesterol 3.63 Triglyceride 0.68 HDL 0.94 LDL 2.27 |
| 5 | Male in his 40s | Smoking | No | PLT 215 HB 150 | PT 13.20 APTT 34.40 TT 14.50 INR 1.02 FIB 3.22 D-dimer 0.00 | Cholesterol 3.93 Triglyceride 1.49 HDL 0.97 LDL 2.24 |
| 6 | Female in her 60s | Hypertension, diabetes mellitus, a history of AIS | No | PLT 411 HB 119 | PT 13.80 APTT 36.10 TT 15.80 INR 1.04 FIB 3.42 D-dimer 1.93 | Cholesterol 3.83 Triglyceride 1.49 HDL 1.11 LDL 2.28 |
| 7 | Male in his 70s | No | No | PLT 400 HB 85 | PT 15.70 APTT 36.90 TT 16.20 INR 1.22 FIB 7.19 D-dimer 5.92 | Cholesterol 3.87 |
| 8 | Female in her 80s | Hypertension, a history of AMI | No | PLT 103 HB 111 | PT 13.40 APTT 36.50 TT 24.00 INR 1.04 FIB 4.96 D-dimer 1.66 | Cholesterol 3.35 Triglyceride 1.95 HDL1.09 LDL 2.49 |
Case 1–5, patients with new-onset ICH following AMI; case 6–8, patients with new-onset AMI following ICH.
PLT=125~350×109/L; HB=115~150 g/L; PT=11~14 s; APTT=28~43.5 s; TT=14~21 s; D-dimer=<0.5 mg/L; INR=0.94~1.30; FIB=2~4 g/L; cholesterol=3.10~5.69 mmol/L; triglyceride=0.56~1.47 mmol/L; HDL=1.16~1.42 mmol/L; LDL=2.07~3.10 mmol/L.
AIS, acute ischemic stroke; AMI, acute myocardial infarction; APTT, activated partial thromboplastin time; FIB, fibrinogen; HB, hemoglobin; HDL, high-density lipoprotein; ICH, intracerebral hemorrhage; INR, international normalized ratio; LDL, low-density lipoprotein; PCI, percutaneous coronary intervention; PLT, platelets; PT, prothrombin time; TT, thrombin time.