Variables | Treatment with SOC | Treatment with MP | P value |
Mean (±SD), median/IQR | N=34 patients | N=24 patients | |
SpO2/FiO2 | 264 (±122) | 267 (±74) | 0.91 |
Respiratory rate (n/min) | 26 (±6) | 24 (±8) | 0.51 |
White cell count (109 c/L) | 6.8/4.7 | 5.15/5.25 | 0.33 |
Lymphocytes (c/μL) | 700/500 | 700/300 | 0.39 |
D-dimers (ng/dL) | 1.2/0.6 | 0.9/0.7 | 0.06 |
CRP (mg/L) | 85.5/72.6 | 67.9/73.4 | 0.17 |
Ferritin (μg/L) | 872/878 | 621/870 | 0.50 |
Fibrinogen (mg/dL) | 669/205 | 612/154 | 0.27 |
LDH (U/L) | 410/188 | 391/188 | 0.83 |
CPK (µg/L) | 106/88 | 162/125 | 0.18 |
Troponin (ng/mL) | 0.01/0.01 | 0.01/0.01 | 0.26 |
PCT (ng/mL) | 0.11/0.11 | 0.08/0.1 | 0.37 |
Fisher’s exact tests.
CPK, creatine kinase; CRP, C reactive protein; LDH, lactate dehydrogenase; MP, methylprednisolone pulse; PCT, procalcitonin; SOC, standard of care.