Thiol-disulfide homeostasis parameters of the study and control groups
| Parameter | CLL mean (n=29) (min–max) | Control mean (n=20) (min–max) | P value |
| Total thiol (µmol/L) | 399.4 (265–501) | 483.1 (443–535) | 0.001* |
| Native thiol (µmol/L) | 348.8 (210–460) | 444.3 (405–492) | 0.001* |
| Disulfide (µmol/L) | 25.3 (13–56) | 18.4 (10–25) | 0.007* |
| Disulfide/Native thiol (%) | 7.76 (3.3–16.5) | 4.1 (2.2–5.6) | 0.001* |
| Disulfide/Total thiol (%) | 6.53 (3.1–12.4) | 3.8 (2.1–5.1) | 0.001* |
| Native thiol/Total thiol (%) | 86.9 (75.2–93.8) | 92.3 (89.9–95.2) | 0.001* |
| IMA (ABSU) | 1.03 (0.34–3.98) | 0.95 (0.47–3.54) | 0.365 |
| TAS (nmol Trolox/L) | 1.34 (1.03–1.62) | 1.48 (1.1–1.97) | 0.104 |
| TOS (μmol H2O2 Eq/L) | 9.1 (5.7–16.8) | 5.15 (7.2–3.1) | 0.001* |
| OSI | 0.67 (0.27–1.40) | 0.35 (0.18–0.49) | 0.001* |
*Mann-Whitney U test.
ABSU, absorbance units; IMA, ischemia-modified albumin; max, maximum; min, minimum; OSI, oxidative stress index; TAS, total antioxidant status; TOS, total oxidant status.